GlyCosmos Portal

Dynein axonemal heavy chain 11

Summary

UniProt ID: E9Q7N9
Gene Symbol: Dnah11 Dnahc11
Gene ID: 13411
Organism: Mus musculus (house mouse)

External Links

GlyGen: E9Q7N9
The O-GlcNAc Database: E9Q7N9
O-GlcNAcAtlas: E9Q7N9
Re-Glyco: E9Q7N9

Annotation

Keyword: ATP-binding Cilium Coiled coil Cytoskeleton Dynein Microtubule Motor protein Proteomics identification Reference proteome Repeat

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
cilium movement	IMP	PMID
epithelial cilium movement involved in extracellular fluid movement	IMP	PMID
regulation of cilium beat frequency	ISO	GO_REF
determination of left/right symmetry	ISO	GO_REF
determination of left/right symmetry	IMP	PMID PMID PMID PMID

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement

epithelial cilium movement involved in extracellular fluid movement

epithelial cilium movement involved in determination of left/right asymmetry

cilium movement involved in cell motility

flagellated sperm motility

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility [inference]

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

reproductive process [inference]

sperm motility [inference]

flagellated sperm motility

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

determination of left/right asymmetry in nervous system

behavior [inference]

learning or memory

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

heart development

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium [inference]

protein localization to motile cilium

establishment of localization [inference]

transport [inference]

extracellular transport [inference]

epithelial cilium movement involved in extracellular fluid movement

epithelial cilium movement involved in determination of left/right asymmetry

microtubule-based transport [inference]

epithelial cilium movement involved in extracellular fluid movement

epithelial cilium movement involved in determination of left/right asymmetry

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of microtubule-based process [inference]

regulation of microtubule-based movement [inference]

regulation of cilium movement [inference]

regulation of cilium beat frequency

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GO Term	Evidence Code	Reference
extracellular region	IEA	GO_REF
microtubule
cilium	IDA	PMID
axoneme	ISO	GO_REF
axoneme	IDA	PMID PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex

catalytic complex [inference]

dynein complex

cellular anatomical structure [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

motile cilium

organelle [inference]

membrane-bounded organelle [inference]

cilium

motile cilium

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

proximal portion of axoneme

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
ATP binding	IEA	GO_REF
minus-end-directed microtubule motor activity	IBA	GO_REF
minus-end-directed microtubule motor activity	IEA	GO_REF
dynein intermediate chain binding	IBA	GO_REF
dynein intermediate chain binding	IEA	GO_REF

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

catalytic activity [inference]

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

polypeptide conformation or assembly isomerase activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

binding [inference]

protein binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity [inference]

minus-end-directed microtubule motor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAAQEEGTVLRLSPSEQEDEEDEEAAAARRVQRFALDPRVRFLGGRLRQALRFPEETWGQYLESDDHRQVLGDFLESTGPASLVFSVATAGRLSASPEIPRDVKHKLVYFAKKMTENMGESDFSQTILFGEIPRSLLTHVTAFLDEILVPVLSNKNNHTSWSCFISQDVEHHTEVMKNKMHIFRGKMSRRTHLPIPTIAENIDLDQHYLVTRPQSDERRILHAIESLVIKWSHQIQEIIEKDSAHPLLSGLHPTPETELDFWTMRHDNLKCIYSQLQAPIVLKMVKILRTRQSSYLPALKGIFTTVENALLEAQDVELHLRPLRRHIHSLQEAEFPQTRILIAPLLHTICLIWSHSKFYNTPARVIVLLQEFCNLFIDQARAYLSPEDLLKGEIEDALEKVQVAISVLKTFQNSFFKYRKGLTSYFTRNTEQRSWDFQSHLVFGRFNKFLDRLVKIEDMFVTILEFEKLERLEFGGSKGAVLNAQIHSTSEEFIECCKVFQQSTYDPSDCDDMEFESDYFKFKSRTLDFDRRLGTLLCEGLSNCSGLESAFKLLTIFGNFLEKPVVMEMFSPHYSTLLNMFNAELDVCKQLYDEHMKQIEHGHEILNKNMPFTSGNIKWARMLLERLQMFWSNFTSLHYLFPDSPDEAAVCQKYAEMTTLLDQFESHIYSEWRRNVDETCEFNLNQPLVKFSPINGLLSVNFDPKLVAVLREVKYLLMLKKSDIPDSALGIFQKRNIILKYIGNLELLVQGYNKLKQTLLEVEYPLIEDELGAIDEQLRVAATWLTWQDDFWVYMERVQVATAELECRVSQTQSNMLTIQQTMQAWAEWPLLPRRETRREAALTLDDKGDLFAKKYKLIREDGCKIHNLVEENRKLFRADPSLDSWKIYVEFIDDIVVEGFFQAILHDLDFFLRNTEKQLKPTPFFQAQMLLMPPEIVFKPPLEKEAGDGFYDLVEEMLCGSFRVSAQMGRVAAHLDIADYQNDMDNMLGLAEVRQEIMNRVADVINKVLEFRSSLETYSYLWVDDRVEILRQFLLYGHAVPSEEMDAPASEDILQPPTLEQFKEQIDIYEALYIQMSKFDDFRVFNSWFKVDMRPFKLSLLNVIKKWSWMFQEHLLRFVVDSLSELQGFIKQTNAGLQRQLCEGDHDGLVDIMGHLLAVRSRQRATDELFEPLKETIMLLESYGQKMPEQVYAQLEELPERWETTKKIAAMVRHEVSPLQNAEVTLIRKKCILFDEKQAEFRERFRSYAPLGFKAENPYAVLDKANQELEALEEEMEQMQNSARLFEVALPEYKQMKQCRQEIRLLKGLWDVIIYVRRSIDNWTETQWRQINVEQMDLELRRFAKEIWSLDKAVRVWDAYSGLEGTVKDMTTSLRAIAELQNPALRDRHWQQLMKAIGVRFSINDSTTLSDLLAVQLHRVEDDVRDIVDQAVKELGTEKVITDVSHTWEALEFSYEAHHRTGTPLLKSDEQLFETLEHNQVQLQSLLQSKYVEYFIEQVLSWQNKLNVADAVIFTWMQVQRTWSHLESIFVCSEDIRVQLVEDARRFDKVDAEFKELMFETAKVKNVLEATCRPHLYEKLKDFQHRLSLCEKALAEYLETKRVTFPRFYFISSADLLDILSKGAQPKQVTHHLVKLFDSISDLQFEDNLDVSTHKAVGMFSKEKEYVPFQAGCECIGHVESWLLQLEQTMKDTVRLAITEAITAYEEKPRELWIFDFPAQVALTGSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELSPGDRQKVMTICTIDVHARDVVAKLISQKVVSPHAFTWLSQLRHEWEDSRKHCVVNICDAHFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYRSIGNIYKGLVQTGAWGCFDEFNRIAVEVLSVVAVQVKMIHDAIRNGRKRFVFLGETIPLKPSVGIFITLNPGYAGRTELPENLKALFRPCAMVAPDTELICEIMLVAEGFVDARSLARKFISLYTLCEELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDVPVFLGLVSDLFPALDVPRQRKPHFEQMVKQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWSDLNPKAVTTDELFGFIHHATREWKDGLFSSILREQANLTHDGPTWIVLDGDIDPLWIESLNTVMDDNKVLTLASNERVALKPSMRLLFETHHLRTATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYIPVCLEKLRTSFKAITSVPESSLVQTICTLLECLLTPENIPPDSPKETYEVYFAFACVWTFGGTLLRDQLSDYQADFSRWWHKEMKAVKFPSQGTIFDYYLDHKTKKFLPWTDKVPQFSMDADAPLKTVLVHTPETTRLRYFTELLLCKGKPIMLVGNAGVGKTVFLSNTLASLSENYIVSCVPFNYYTTSAALQRILEKPLEKKAGRNYGPKGNKKLVYFIDDLNMPEVDLYGTIQPHALLRQHIDYGHWYDRHKIMLKEIRNCQYVACMNPMVGSFTVNPRLQRHFTVFAFNFPSLDALTTIYGQIFSFYLQQQAFCPSVLRAGPSLIQATIAFHQMMAESFVPTAIKFHYNFNLRDLSNIFQGILFASPECLKSLEDLARLWLHETSRVYGDRLIDTNDFDLFQRKMLETAHKYFKGVDANALLRQPLVYCHFASGGEDPCYMPVKDWEGLKAVLMEMVDNYNELHSAMHLVLFEDAMQHVCRISRILRIPQGHALLIGVGGSGKQSLSRLAAYICSLEVFQITLTEGYGAQELRVDLANLYVRTGAKNMPTVFLLTDAHVLDESFLVLINDLLASGDIPDLFSDEDMDKIISGIRNEVRGLGLVDSRENCWAFFLARVRQQLKMVFCFSPVGHTLRVRARKFPAIVNCTAIDWFHEWPQEALVSVSRRFIEEIEGIEPQHKDSISLFMAHVHTSVKEVSAWYYQNERRYNYTTPRSFLEQISLFKSLLKKKREEVKQKQEHLGNGIQKLQTTASQVGNLKSRLASQEAELQLRNLDAEALITKIGLQTEKVSREKAIADAEERKVAAIQTEASQKQRECEADLLKAEPALVAAKDALNTLNRVNLTELKTFPNPPNAVTNVTAAVMVLLAPRGRVPKDRSWKAAKIFMGKVDDFLQALINYDKEHIPENCLKVVNEQYLKDPEFNPNLIRTKSFAAAGLCAWVINIIRFYEVYCDVEPKRQALAQTNLDLAAATEKLEAVRRKLVDLDHNLSRLTASFEKATAEKVRCQEEVNQTNKTIDLANKLVSELESEKIRWGQSIKSFETQEKTLCGDVLLTAAFVSYIGSFTRQYRQELVDCKWIPFLQQKVSIPIAEGLDLIAMLTDDATIATWNNEGLPSDRMSTENATILTHCERWPLMIDPQQQGIKWIKNKYGPDLKVTHLGQKGFLNTIETALAFGDVILIENLKETVDPVLGPLLGRNTTKKGKFIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEGQLLAEVVSIERPDLERLKLVLTKQQNDFKIELRQLEDDLLLRLSAAEGSFLDDTDLVERLETTKATAAEIEHKVTEARENERKINETRECYRPVAARASLLYFVISDLRRINPVYQFSLKAFNTLFHRAIEQADKVEDTQERICALIESITHATFLYASQALFERDKLTFLSQMAFQILLRRNEIHPLELDFLLRFTVEHTYSSPVDFLTAQSWSAVKAVALMEEFRGLDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLIILRAVRPDRMTYALRNFVEEKLGAKYVERTRLDLGKAFEESSPSTPVFFILSPGVDALKDLEVLGKRLGFTIDSGKFHNVSLGQGQELVAEMAMEKAAAGGHWVILQNVHLVAKWLGTLEKLLEKFSQGSHRDYRVFLSAETVPSQHEPIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEMCSKDQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFSPGDLTICTNILYNYLEANPNVPWEDLRYLFGEIMYGGHITDAWDRKLCRVYLEEFMNPSLIEDEVMLAPGFAAPPYSDYSGYHQYIEDTLPPESPALYGLHPNAEIELLTVTSNTLFRTLLEMQPRNAVSQEELGQSTEDKVKNILDDILERLPEEFNMAEIMQKNPNRSPYVLVCFQECERMNVLIREIRVSLQHLDLGLKGELTLSPDVETQLSALSYDRVPDTWNKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDRMCLTIDVTKKTKEDYGHPPREGAYLHGLHLEGARWDIQSGALVDARLKELTSMMPVIFAKAVPVDRQEIKHAYECPVYKTKARGPTYVWTFRLRSKDRIAKWVLAGVALLLEA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
1799		30059200	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Disease

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050651	atrioventricular septal defect	Alliance of Genome Resources
DOID:0050545	visceral heterotaxy	Alliance of Genome Resources
DOID:0110605	primary ciliary dyskinesia 7	Alliance of Genome Resources
DOID:0050144	Kartagener syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements