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Laminin subunit alpha-5

Summary

UniProt ID: F1MAN8
Gene Symbol: Lama5
Gene ID: 140433
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: F1MAN8
Re-Glyco: F1MAN8

Annotation

Keyword: Basement membrane Cell adhesion Coiled coil Disulfide bond Glycoprotein Laminin EGF-like domain Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 38 in total

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GO Term	Evidence Code	Reference
branching involved in ureteric bud morphogenesis	ISO	GO_REF
morphogenesis of a polarized epithelium	ISO	GO_REF
morphogenesis of a polarized epithelium	IEA	GO_REF
neural crest cell migration	ISO	GO_REF
kidney development	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cell motility [inference]

cell migration

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

trunk neural crest cell migration

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

postsynapse organization

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

molting cycle process [inference]

hair cycle process [inference]

hair follicle development

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

animal organ morphogenesis

odontogenesis [inference]

odontogenesis of dentin-containing tooth

skeletal system morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

anatomical structure development [inference]

animal organ development [inference]

muscle structure development [inference]

muscle organ development

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of cell adhesion

regulation of cell population proliferation [inference]

regulation of epithelial cell proliferation

regulation of cell motility [inference]

regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
basement membrane	ISO	GO_REF
basement membrane	IBA	GO_REF
basement membrane	IEA	GO_REF GO_REF
laminin-332 trimer
obsolete extracellular space

GO Hierarchy

cellular component

protein-containing complex [inference]

extracellular protein-containing complex [inference]

laminin trimer [inference]

cellular anatomical structure [inference]

cell junction [inference]

synapse [inference]

external encapsulating structure [inference]

extracellular matrix

basement membrane

specialized extracellular matrix [inference]

extracellular matrix of synaptic cleft

synaptic cleft

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
integrin binding	ISO	GO_REF
integrin binding	IEA	GO_REF GO_REF
extracellular matrix structural constituent	IBA	GO_REF
receptor ligand activity	ISO	GO_REF
receptor ligand activity	IEA	GO_REF

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

protein-containing complex binding [inference]

integrin binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAKRGGQLCVGCAPGARGPRSLAPLPLLLLAGLALVGEARIPGGDGFSLHPPYFNLAEGARITASATCGEEAPTRSASRPTEDLYCKLVGGPVAGGDPNQTIQGQYCDICIAANSNKAHPVSNAIDGTERWWQSPPLSRGPEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSTDFGHTYQPWQFFASSKRDCLERFGPRTLERITQDDDVICTTEYSRIVPLENGEIVVSLVNGRPGARNFSYSPVLRDFTKATNIRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHADVCDAKDPSDPFRLQCACQHNTCGGSCDRCCPGFNQQPWKPATTDSANECQSCNCHGHAYDCYYDPEVDRRNASQNLDNVYQGGGVCLDCQHHTTGINCERCVPGFYRAPDQPLDSPHVCQPCDCESDFTDGTCEDLTGRCYCRPNFTGERCSACAEGYVDFPHCYPLPSFPHNDTGEQVLPAGQIVNCDCNAAGTQGNACRKDPRLGRCVCKPNFQGNHCELCAPGFYGPSCHPCQCSSPGVANGLCDPESGQCTCRTGFEGDKCDHCALGYFHFPLCQLCGCSPAGTLPQGCDESGHCQCRPGFDGPHCDRCLPGYHGYPDCHACACDPRGSLDQQCGAGGLCHCRPGYTGATCQECSPGFYGFPSCIPCHCSADGSMHTTCDPTTGQCRCRPRVTGLRCDMCVPGAYNFPYCEAGSCHPAGLAPANPALPEAQAPCTCRAHVEGPSCDRCKPGYWGLSSSNPEGCTRCSCDPRGTLGGVTECQGNGQCFCKAHVCGKTCAACKDGFFGLDHADYYGCRSCRCDVGGALGQGCEPKTGACRCRPNTQGPSCSEPAKDHYLPDLHHIRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAHMTAIQPRIVARLNVTSPDLFRLVFRYVNRGSTSVNGQVSVREEGKFSSCTNCTEQSQPVAFPPSTEPAFVTVPQRGFGEPFVLNPGTWALLVEAEGVLLDYVVLLPSTYYEAALLQHRVTEACTYHPSALHPTENCLLYAHLPLDGFPSAAGTEALCRHDNSLPRPCPTEQLSPLHPPLATCAGSDVDIQLEMAVPRPGRYALVVEYVSEYSHQEMGVAVHTPQRAPQQGMIDLHPCPYSSLCRGPARDTQHHLAVFHLDSEASIRLTAEQAHFFLHSVTLIPVEEFSAEFVEPRVFCVSSHGAFNPGSAACLASRFPKPPQPIVLKDCQVLPLPPDLPLTQSQELSPGASPVGPQPRPPTAVDPNAEPTLIRHPQGTVVFTTQVPTLGRYAFLLHSYQPVHPSFPVEVLIDGGRIWQGHANASFCPHGYGCRTLVSCEGQTMLDVTDNELAVTVRVPEGRWLWLDYILVVPEDAYSSSYLQEEPLDKSYDFISHCATQGYHISPSSSSLFCRNAATSLSLFYNNGALPCGCHEVGAVGPTCEPFGGQCPCRGHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTVPPDCLVCQPQSFGCHPLVGCEECNCSGPGVQELTDPTCDMDSGQCRCRPNVAGRRCDTCAPGFYSYPSCRPCDCHEAGTMASVCDPFTGQCHCKENVQGSRCDQCRVGTFSLDAANPKGCTRCFCFGATERCGNSNYARHEFMDMEGWVLLSSDRQVVPHEHRPEMELLHADLRLVADTFPELYWQAPPSYLGDRVSSYGGTLHYELHSETRRGDVFIPYESRPDVVLQGNQMSIAFLELAYPSPGQVHRGQLQLVEGNFRHLETHNPVSREELMMVLAGLEQLQIRALFSQTSSTVSLRRVVLEVASEAGGGPPASNVELCMCPANYRGDSCQECAPGYYRDTKGLFLGRCVPCQCHGHSDRCLPGSGTCVGCQHNTEGDQCERCRPGFVSSDPSDPASPCVSCPCPLAVPSNNFADGCILRNGRTQCLCRPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNMIFSDCDPLTGACRGCLRHTTGPRCESCAPGFYGNALLPGNCTRCDCSPCGTETCDPQTGRCLCKAGVTGQRCDHCLEGHFGFEQCQGCHPCACGPAAEGSECNPQTGQCHCRPGTTGPQCLECAPGYWGLPEKGCRRCQCPRGHCDPHTGRCTCPPGLSGERCDTCSQQHQVPVPGRPGSHGIHCEVCDHCVVLLLDDLERAGALLPSIREQLRGINASSTAWARLHRLNASIADLQSKLRSPLGPHNQTAEQLQTLEQQSISLQQDTERLGSQATGVQDQAGRLLDNTESTLVRAQKLLEIVQAVSRALNELASQGFPGNATTPSGEQLRWALAEVERLLWDMRTRDLGAPQAVAEAELAEAQRLMARVQEQLTSFWEENQALATHIRDQLAQYESGLMDLREALNHAVNTTREADELNSRNEERLREALQWKQELSQDNATLKATLQAASLTLAHVSELLQGIDKAKEDLEHLAASLDGAWTPLLKRMQAFSPASSKVDLVEAAEAHAQKLNQLAINLSGIIQGINQDRFIQRAVEASNAYSSILQAVQAAEDAAGHALRQASRTWEMVVQRGLAAGARQLLANSSALVETILGHQERLGLAHGRLQAAGTQLRDVRAKKNQLAAQIQEAQAMLAMDTSETSEKIAHAKAVAAEARDTAAHVQSQLQGMQKNVERWQSQLGGLRGQDLSQAERDASSSVSTLEKTLPQLLAKLSHLENRGVHNASLALSANIGRVRKLIAQARSAANKVKVSMKFNGRSGVRLRTPRDLADLAAYTALKFYIQSPVPAPEPGENTGDRFVLYMGSRQATGDYMGVSLRNQKVHWVYRLGEAGPTTLSIDENIGEQFAAVSIDRTLQFGHMSVTVEKHMVHEIKGDTVAPGREGLLNLNPDDFVFYVGGYPSNFTPPEPLRFPGYLGCIEMDTLNEEVVSLYNFEQAFKLTTAVDKPCARSKTTGDPWLTDGSYLDGSGFARITFEKQFSNTKRFEQELRLVSYNGIIFFLKQENQFLCLAVQDGTLVLLYDFGSGLKRADPLQPPQALTAASKAIQVFLLAGARKRVLVRVERATVFSVDQDNELEMADAYYLGGVPPEELPPSLRRLFPSGGSVRGCIKGIKALGKYVDLKRLNTTGISFSCTADLLMGRTMTFHGHGFLPLALPDVAPITGEVYSGFGFRGTQDDNLLYYRTSPDGPYQVSLRGGHVTLQFMNREVETQRVFADGAPHYVAFYSNVTRVWLYVDDQLQPVKSREGTTPMLQLQPEEPPRLLLGGLPMSGTFHNFSGCISNVFVQRLRGPQRVFDLHQNMGSVNVSVGCTPAQLQTSGATAQKVSRRSRQPSQDLTCMTPWLLGTIQDAYQFGGPGPSYLQFVGVSPSHRNRLHLSMLVRPHGASQGLLLYVAPLSSHSPSLVLFLNHGRFVAQTEGPGPQLQAQSRQHSRAGQWHRVSVRWGMQQVQLVVDGSQTWSQKAPHRRVHRAEGPQHYTLFVGGLPAGSYSSKLPVSVGFSGCMKKLQLDKRPLRAPTRMVGVTPCVSGPLEDGLFFPGSEGAVTLELPKAKMPHVSLELEVRPLAAAGLIFHLGQAHATPYVQLQLLTEQVLLRANDGAGEFSTWVTYPKLCDGQWHQVTVIKGRNTLRLEVDTHSNHTTGRLPETLADSPALLHLGSPPKSEAAWPEPPAYRGCLRKLLFNGAPVNMTASARIQGAVGMSGCPSGTLAISKQGKALTQRQANPSVFPLRWH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 11 in total

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Position	PubMed ID	GlyTouCan ID	Source
247	24090084	G62765YT G31852PQ	GlyGen
1334	24090084	G80920RR G62765YT G31852PQ G41247ZX	GlyGen
1453			GlyGen
2210	24090084	G88374WZ G02815KT	GlyGen
2391	24090084	G02815KT	GlyGen
2421	24090084	G02815KT	GlyGen
2566	24090084	G85740DB G02815KT G55220VL	GlyGen
3209	24090084	G49018RC G02815KT	GlyGen
3257	24090084	G80920RR	GlyGen
3287	24090084	G31852PQ G41247ZX G02815KT	GlyGen