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Frizzled-2
Summary
- UniProt ID
- G5ECQ2
- Gene Symbol
-
- F27E11.3
- cfz-2
- Gene ID
- 178768
- Organism
- Caenorhabditis elegans
Annotation
- Keyword
-
- Cell membrane
- Developmental protein
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Neurogenesis
- Reference proteome
- Signal
- Transmembrane helix
- Wnt signaling pathway
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| GO Term |
|---|
| Wnt-protein binding |
| Wnt receptor activity |
| G protein-coupled receptor activity |
Sequence
MLLRISVLFLLLGSCGALFGKRQKCEQITIPLCKGIGYNMTSFPNSYGHEKQEEAGLEVHQFYPLVEVGCFQHLKFFLCTMYTPICQENYDKPILPCMELCVEARSKCSPIMAKYGFRWPETLSCEALPKMSDQMSTGNICAAPPDTPKKQHKGHHHKNQNQNQNQNHNYSPDGPEVGISKIDNEVIAGPSECQCTCNQPFQFVASEKSKVGNVTNCAYSCHSPALAESHSLVSNWMAFWSITCCVLASFTFLTFLIETDRFQYPERPIFMLAFCQLMVAVGFMIRYFVGHEEIACDSMRIKGADDNSGSLCFVVFLLTYFFGMAASVWWVILSLTWVLSAASKWSPEAISSFSFHFHVVGWCLPAIQTVLVIVFNAIDGDPITGICYVGNTDLQFQRIFVLFPLLVYFIVGVLFLVIGFCNLWSIRNEVQKQHPSLESAHKITQLMSKIGIFSLLYTIPSLLIICVLFYEQNHRSLWEQSQLCSCSPKQTIGDSSLIISLIKTCCMCILGWTSGFWVCSTKTLSSWKNAICCLGSSRSLPKYQPADILYAKSDMSSSQFYNTSLRHNHLYGGIPDKL
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Asymmetric localization of PCP proteins | Caenorhabditis elegans |
| Ca2+ pathway | Caenorhabditis elegans |
| Disassembly of the destruction complex and recruitment of AXIN to the membrane | Caenorhabditis elegans |
| Regulation of FZD by ubiquitination | Caenorhabditis elegans |
| WNT5A-dependent internalization of FZD2, FZD5 and ROR2 | Caenorhabditis elegans |
