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Carboxylic ester hydrolase

Summary

UniProt ID: G5EDV9
Gene Symbol: ace-2 CELE_Y44E3A.2 Y44E3A.2
Gene ID: 171905
Organism: Caenorhabditis elegans

External Links

GlycoProtDB: GPDB0000199
Re-Glyco: G5EDV9

Annotation

Keyword: Disulfide bond Reference proteome Serine esterase

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
acetylcholine catabolic process in synaptic cleft	IC	PMID
acetylcholine catabolic process	IDA	PMID
acetylcholine catabolic process	IMP	PMID
acetylcholine catabolic process	IBA	GO_REF
synaptic transmission, cholinergic	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, cholinergic

metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine catabolic process

acetylcholine catabolic process in synaptic cleft

catabolic process [inference]

acetylcholine catabolic process

acetylcholine catabolic process in synaptic cleft

choline metabolic process

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, cholinergic

regulation of locomotion

Displaying **all 4** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
plasma membrane	IBA	GO_REF
synaptic cleft	IEA	GO_REF
synapse	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

synaptic cleft

Displaying **all 5** entries
GO Term	Evidence Code	Reference
acetylcholinesterase activity	IDA	PMID
acetylcholinesterase activity	IMP	PMID
acetylcholinesterase activity	IBA	GO_REF
identical protein binding	IPI	PMID
protein homodimerization activity	IPI	PMID

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

cholinesterase activity [inference]

acetylcholinesterase activity

binding [inference]

protein binding [inference]

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRAPVIGRHLTYHVFCQFALVTLFIVRRIEPRSIVRGDHVVHTPLGTIRGVGQTFDGAKVSAFLGVPYAKPPIGSRRFKMAEMIDRWSGELEARTLAKTCYLTIDSAFPQFPGAEMWNPPGAISEDCLNMNIWVPEDHDGSVMVWIYGGGFFSGTPSLDLYSGSVFAAKEHTIVVNVNYRLGPFGFLYFGDDSPIQGNMGLMDQQLALRWVHENIGAFGGDRSRVTLFGESAGSASTTAHLFAPNSHKYFRNIIAKSGSIINSWASATPPTMLDLSFRLAKKVNCSSPDMNAIVKCLRSVPAHLVQAEADNISGDIGPPMTFAYVPVSSDANFFQGDVFQKLANKQFKKDVNIIFGSVKDEGTYWLPYYMSLPKYGFAFNHTISAEDPHNRALITRDHYEESMRAFMPYFAGSKLVLNAFMNSYEHVSTSNVPEERYRDGVARFLGDLFFTCSLIDFADLISDNIFGNVYMYYFTYRSSANPWPKWMGVMHGYEIEYAFGQPYWRPHLYDQTHLEDEKRLSSIIMQIWANFANTGRTDSFWPQYNKIERKAIELGETTLQGKHRIISDVHGGFCRMIDEAKAFVKQKNANDCRTTRKSASTEDLTSSSSTTYLFSIIVYLSILISYISL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites