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Semaphorin-4D

Summary
UniProt ID
O09126
Gene Symbol
  • Sema4d
  • Semacl2
  • Semaj
Gene ID
20354
Organism
Mus musculus (house mouse)
GlycoProtDB
GPDB0003071
GlyConnect
GlyGen
O09126
PubChem
O09126
Re-Glyco
O09126
Annotation
Keyword
  • Cell membrane
  • Developmental protein
  • Differentiation
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Neurogenesis
  • Phosphoprotein
  • Reference proteome
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 5 entries
GO Term
extracellular space
membrane
semaphorin receptor complex
GABA-ergic synapse
postsynaptic membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MRMCAPVRGLFLALVVVLRTAVAFAPVPRLTWEHGEVGLVQFHKPGIFNYSALLMSEDKDTLYVGAREAVFAVNALNISEKQHEVYWKVSEDKKSKCAEKGKSKQTECLNYIRVLQPLSSTSLYVCGTNAFQPTCDHLNLTSFKFLGKSEDGKGRCPFDPAHSYTSVMVGGELYSGTSYNFLGSEPIISRNSSHSPLRTEYAIPWLNEPSFVFADVIQKSPDGPEGEDDKVYFFFTEVSVEYEFVFKLMIPRVARVCKGDQGGLRTLQKKWTSFLKARLICSKPDSGLVFNILQDVFVLRAPGLKEPVFYAVFTPQLNNVGLSAVCAYTLATVEAVFSRGKYMQSATVEQSHTKWVRYNGPVPTPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPKLIKKDVNYTQIVVDRTQALDGTFYDVMFISTDRGALHKAVILTKEVHVIEETQLFRDSEPVLTLLLSSKKGRKFVYAGSNSGVVQAPLAFCEKHGSCEDCVLARDPYCAWSPAIKACVTLHQEEASSRGWIQDMSGDTSSCLDKSKESFNQHFFKHGGTAELKCFQKSNLARVVWKFQNGELKAASPKYGFVGRKHLLIFNLSDGDSGVYQCLSEERVRNKTVSQLLAKHVLEVKMVPRTPPSPTSEDAQTEGSKITSKMPVASTQGSSPPTPALWATSPRAATLPPKSSSGTSCEPKMVINTVPQLHSEKTVYLKSSDNRLLMSLLLFIFVLFLCLFSYNCYKGYLPGQCLKFRSALLLGKKTPKSDFSDLEQSVKETLVEPGSFSQQNGDHPKPALDTGYETEQDTITSKVPTDREDSQRIDELSARDKPFDVKCELKFADSDADGD
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying entries 1 - 10 of 11 in total
Position Description PubMed ID GlyTouCan ID Source
49 N-linked (GlcNAc...) asparagine
77 N-linked (GlcNAc...) asparagine
139 N-linked (GlcNAc...) asparagine
191 N-linked (GlcNAc...) asparagine
364
379 N-linked (GlcNAc...) asparagine
419 N-linked (GlcNAc...) asparagine
613 N-linked (GlcNAc...) asparagine
632 N-linked (GlcNAc...) asparagine
657
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Other semaphorin interactions Mus musculus
Sema4D induced cell migration and growth-cone collapse Mus musculus
Sema4D mediated inhibition of cell attachment and migration Mus musculus
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025