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Neurosecretory protein VGF

Summary

UniProt ID: O15240
Gene Symbol: VGF
Gene ID: 7425
Organism: Homo sapiens (human)

External Links

GlyGen: O15240
PubChem: O15240
RaftProt: O15240
Re-Glyco: O15240

Annotation

Keyword: 3D-structure Amidation Antibiotic Cleavage on pair of basic residues Cytoplasmic vesicle Direct protein sequencing Growth factor Phosphoprotein Proteomics identification Pyrrolidone carboxylic acid Reference proteome Secreted Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
ovarian follicle development
response to dietary excess
generation of precursor metabolites and energy
response to cold
insulin secretion

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

insulin secretion

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis [inference]

response to dietary excess

developmental process [inference]

anatomical structure development [inference]

ovarian follicle development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

energy homeostasis [inference]

response to dietary excess

chemical homeostasis [inference]

carbohydrate homeostasis

glucose homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to bacterium

response to cold

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to cold

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to nutrient levels [inference]

response to dietary excess

response to chemical [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to organophosphorus [inference]

response to cAMP

response to nitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to insulin

response to cAMP

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

establishment of localization [inference]

transport [inference]

hormone transport [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

protein transport [inference]

protein secretion [inference]

insulin secretion

peptide transport [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

insulin secretion

secretion [inference]

peptide secretion [inference]

peptide hormone secretion [inference]

insulin secretion

secretion by cell [inference]

protein secretion [inference]

insulin secretion

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

nitrogen compound transport [inference]

peptide hormone secretion [inference]

insulin secretion

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

insulin secretion

signal release [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion [inference]

insulin secretion

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

insulin secretion

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone transport [inference]

hormone secretion [inference]

peptide hormone secretion [inference]

insulin secretion

regulation of synaptic plasticity

Displaying **all 5** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
endoplasmic reticulum lumen	TAS	Reactome Reactome
Golgi apparatus	IDA	GO_REF
transport vesicle	IEA	GO_REF
cytoplasmic vesicle	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle

transport vesicle

Displaying **all 3** entries
GO Term	Evidence Code	Reference
hormone activity	IBA	GO_REF
neuropeptide hormone activity	IEA	GO_REF GO_REF
growth factor activity

GO Hierarchy

molecular function

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

neuropeptide hormone activity

growth factor activity

neuropeptide activity [inference]

neuropeptide hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

neuropeptide hormone activity

growth factor activity

neuropeptide activity [inference]

neuropeptide hormone activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKALRLSASALFCLLLINGLGAAPPGRPEAQPPPLSSEHKEPVAGDAVPGPKDGSAPEVRGARNSEPQDEGELFQGVDPRALAAVLLQALDRPASPPAPSGSQQGPEEEAAEALLTETVRSQTHSLPAPESPEPAAPPRPQTPENGPEASDPSEELEALASLLQELRDFSPSSAKRQQETAAAETETRTHTLTRVNLESPGPERVWRASWGEFQARVPERAPLPPPAPSQFQARMPDSGPLPETHKFGEGVSSPKTHLGEALAPLSKAYQGVAAPFPKARRPESALLGGSEAGERLLQQGLAQVEAGRRQAEATRQAAAQEERLADLASDLLLQYLLQGGARQRGLGGRGLQEAAEERESAREEEEAEQERRGGEERVGEEDEEAAEAEAEAEEAERARQNALLFAEEEDGEAGAEDKRSQEETPGHRRKEAEGTEEGGEEEDDEEMDPQTIDSLIELSTKLHLPADDVVSIIEEVEEKRKRKKNAPPEPVPPPRAAPAPTHVRSPQPPPPAPAPARDELPDWNEVLPPWDREEDEVYPPGPYHPFPNYIRPRTLQPPSALRRRHYHHALPPSRHYPGREAQARRAQEEAEAEERRLQEQEELENYIEHVLLRRP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 14 in total

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Position	PubMed ID	GlyTouCan ID	Source
95	30459171	G43417UB	GlyGen
180	23584533	G57321FI	GlyGen
185	23584533	G57321FI	GlyGen
187	23584533	G57321FI	GlyGen
189	23584533	G57321FI	GlyGen
191	23584533	G57321FI	GlyGen
193	23584533	G57321FI	GlyGen
208	23584533	G57321FI	GlyGen
247	23584533	G57321FI	GlyGen
252	23584533	G57321FI	GlyGen