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Neprilysin-11

Summary

UniProt ID: O16796
Gene Symbol: F18A12.8 nep-11
Gene ID: 173685
Organism: Caenorhabditis elegans

External Links

GlycoProtDB: GPDB0000409
Re-Glyco: O16796

Annotation

Keyword: Alternative splicing Cell membrane Disulfide bond Glycoprotein Metal-binding Metalloprotease Reference proteome Signal-anchor Transmembrane helix Zinc

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	Reference
protein processing	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

protein maturation [inference]

protein processing

Displaying **all 2** entries
GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	Reference
metalloendopeptidase activity	IBA	GO_REF
metalloendopeptidase activity	IEA	GO_REF
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPFGNDPPDYVHLRSNESQMQLITISENSDIPTPSGSPCFNAPARDEAPSVIFIPGKKFQGTFRWWKSRTTMEKLLLPVLLLFCLLTAVLLAVIINTDKRIEAMKTDHATQTEHAGFGDPTENPTKTAEDPRVPPIVPEAPTSPEPEVTTSTEKPKEPEVCSTPGCVRAATHFLNAMNTSVDPCDDFFEFACGQWNDQHPIPDDMYGFGTFAYAREQVRQQLRVLLEQEVVTESESINMARATYRSCMNKTQLDELMTGPLFETLTELGEWPLLQENWDKTKFNFTSLLVNSRRDYGVDVFFQLYIYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERRNNTRLYNKRQIQDLYNLLPQVDWVPFFQSIAPSDLTHLFHNETEIIICEIEYLQHVSELIEKTDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYVQAHFQESDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANSMINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFDKHEFDISPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTRRRCIVEQYGNYTVPKTNFRVNGKLTQGENIADNGGVKEAFQAYQKYVTENGEEPRLPGLQQYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKCPRNAPVNPDHKCIVW

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	PubMed ID	Source
178	N-linked (GlcNAc...) asparagine		UniProt
249	N-linked (GlcNAc...) asparagine		UniProt
284	N-linked (GlcNAc...) asparagine		UniProt
312	N-linked (GlcNAc...) asparagine		UniProt
337	N-linked (GlcNAc...) asparagine		UniProt
364	N-linked (GlcNAc...) asparagine		UniProt
398	N-linked (GlcNAc...) asparagine		UniProt
438	N-linked (GlcNAc...) asparagine		UniProt
726	N-linked (GlcNAc...) asparagine	12754521 17761667	GlycoProtDB UniProt