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Lysosome membrane protein 2

Summary

UniProt ID: O35114
Gene Symbol: Scarb2
Gene ID: 12492
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003082

GlyConnect

Lysosome membrane protein 2

GlyGen

O35114

PubChem

O35114

The O-GlcNAc Database

O35114

RaftProt

O35114

Re-Glyco

O35114

Annotation

Keyword: Direct protein sequencing Disulfide bond Glycoprotein Lysosome Palmitate Receptor Reference proteome Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
protein targeting to lysosome	ISO	GO_REF
protein targeting to lysosome	IMP	PMID PMID
protein targeting to lysosome	IBA	GO_REF
protein targeting to lysosome	IEA	GO_REF
receptor-mediated endocytosis	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

autophagy

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

endosome to plasma membrane protein transport

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport [inference]

protein targeting to lysosome

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

process utilizing autophagic mechanism [inference]

autophagy

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

endosome to plasma membrane protein transport

protein localization to organelle [inference]

protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to lysosome [inference]

protein targeting to lysosome

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of localization [inference]

transport [inference]

lipid transport [inference]

phospholipid transport [inference]

aminophospholipid transport

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

endosome to plasma membrane protein transport

organophosphate ester transport [inference]

phospholipid transport [inference]

aminophospholipid transport

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

endosome to plasma membrane protein transport

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport [inference]

protein targeting to lysosome

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

nitrogen compound transport [inference]

aminophospholipid transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

endosome to plasma membrane protein transport

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

endosome to plasma membrane protein transport

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport [inference]

protein targeting to lysosome

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

endosome to plasma membrane protein transport

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport [inference]

protein targeting to lysosome

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of carbohydrate catabolic process

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of carbohydrate catabolic process

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

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GO Term	Evidence Code	Reference
lysosomal membrane	ISO	GO_REF
lysosomal membrane	IDA	PMID
lysosomal membrane	IBA	GO_REF
lysosomal membrane	IEA	GO_REF GO_REF
plasma membrane	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endocytic vesicle membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	Reference
phosphatidylserine binding	IDA	PMID
scavenger receptor activity	IDA	PMID
scavenger receptor activity	IBA	GO_REF
scavenger receptor activity	IEA	GO_REF
cholesterol binding	IDA	PMID

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

protein-folding chaperone binding

lipid binding [inference]

steroid binding [inference]

sterol binding [inference]

cholesterol binding

phospholipid binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

phosphatidylserine binding

cation binding [inference]

phosphatidylcholine binding

alcohol binding [inference]

cholesterol binding

quaternary ammonium group binding [inference]

phosphatidylcholine binding

modified amino acid binding [inference]

phosphatidylserine binding

cargo receptor activity

scavenger receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQTIEKNMVLQNGTKVFNSWEKPPLPVYIQFYFFNVTNPEEILQGEIPLLEEVGPYTYRELRNKANIQFGENGTTISAVTNKAYVFERNQSVGDPNVDLIRTINIPLLTVVDLAQLTLLRELIEAMLKAYQQKLFVIHTVHELLWGYKDEILSLVHIFKPDVSPNFGLFYERNGTNDGEYVFLTGEDNYLNFSKIVEWNGKTSLDWWTTDTCNMINGTDGDSFHPLISKDEVLYLFPSDLCRSVHITFSSFENVEGLPAFRYKVPAEILANTSENAGFCIPEGNCMDSGVLNISICKNGAPIIMSFPHFYQADEKFVSAIKGMHPNKEEHESFVDINPLTGIILRGAKRFQINTYVRKLDDFVETGDIRTMVFPVMYLNESVLIDKETANQLKSVINTTLVVTNIPYIIMALGVFFGLVFTWLACRGQGSMDEGTADERAPLIRT

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 12 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
45	N-linked (GlcNAc...) asparagine		G06247RL	GlycoProtDB UniProt GlyGen
68	N-linked (GlcNAc...) asparagine			UniProt GlyGen
105	N-linked (GlcNAc...) asparagine	19349973	G40926MX	GlycoProtDB UniProt GlyGen
122	N-linked (GlcNAc...) asparagine	30899004	G86339HP G23294PN G70101JE G64527OM G05724UK G39188ZX G06110VR G66538GV	GlycoProtDB UniProt GlyGen GlyConnect
124		37507081 40885482	G49108TO	The O-GlcNAc Database
206	N-linked (GlcNAc...) asparagine			UniProt GlyGen
224	N-linked (GlcNAc...) asparagine			UniProt GlyGen
249	N-linked (GlcNAc...) asparagine			UniProt GlyGen
304	N-linked (GlcNAc...) asparagine		G40508QH	GlycoProtDB UniProt GlyGen
325	N-linked (GlcNAc...) asparagine			GlycoProtDB UniProt GlyGen