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MIRAGE
Vesicular acetylcholine transporter
Summary
- UniProt ID
- O35304
- Gene Symbol
- Slc18a3 Vacht
- Gene ID
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- Cytoplasmic vesicle Glycoprotein Neurotransmitter transport Reference proteome Synapse Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| chemical synaptic transmission | ||
| positive regulation of acetylcholine secretion, neurotransmission | ||
| acetylcholine transport | ||
| serotonin uptake | ||
| acetylcholine uptake |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| cytoplasm | ||
| synaptic vesicle | ||
| AP-1 adaptor complex | ||
| AP-1 adaptor complex | ||
| AP-2 adaptor complex |
| GO Term | Evidence Code | Reference |
|---|---|---|
| acetylcholine transmembrane transporter activity | ||
| acetylcholine transmembrane transporter activity | ||
| acetylcholine:proton antiporter activity | ||
| acetylcholine:proton antiporter activity | ||
| monoamine transmembrane transporter activity |
GO Hierarchy
Sequence
MEPTAPTGQARAAATKLSEAVGAALQEPQRQRRLVLVIVCVALLLDNMLYMVIVPIVPDYIAHMRGGSESPTLISEVWEPTLPPPTLANASAYLANTSASPTAAGSARSILRPRYPTESEDVKIGVLFASKAILQLLVNPLSGPFIDRMSYDVPLLIGLGVMFASTVMFAFAEDYATFFAARSLQGLGSAFADTSGIAMIADKYPEEPERSRALGVALAFISFGSLVAPPFGGILYEFAGKRVPFLVLAAVSLFDALLLLAVAKPFSAAARARANLPVGTPIHRLMLDPYIAVVAGALTTCNIPLAFLEPTIATWMKHTMAASEWEMGMVWLPAFVPHVLGVYLTVRLAARYPHLQWLYGALGLAVIGVSSCVVPACRSFAPLVVSLCGLCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYSVAYALGPIVAGHIVHSLGFEQLSLGMGLANLLYAPVLLLLRNVGLLTRSRSERDVLLDEPPQGLYDAVRLREVQGKDGGEPCSPPGPFDGCEDDYNYYSRS
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Acetylcholine Neurotransmitter Release Cycle | Mus musculus |
| Cargo recognition for clathrin-mediated endocytosis | Mus musculus |
| Clathrin-mediated endocytosis | Mus musculus |
