GlyCosmos Portal

Submissions

5'-3' exonuclease PLD3

Summary

UniProt ID: O35405
Gene Symbol: Pld3 Sam9
Gene ID: 18807
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003106

GlyConnect

Phospholipase D3

GlyGen

O35405

PubChem

O35405

Re-Glyco

O35405

Annotation

Keyword: 3D-structure Disulfide bond Endoplasmic reticulum Endosome Exonuclease Glycoprotein Golgi apparatus Inflammatory response Innate immunity Lysosome Magnesium Metal-binding Phospholipid metabolism Reference proteome Repeat Signal-anchor Transmembrane helix Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	Reference
lipid metabolic process
inflammatory response
myotube differentiation	ISO	GO_REF
innate immune response	ISS	GO_REF
innate immune response	ISO	GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process

cellular developmental process [inference]

cell differentiation [inference]

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

myotube differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

myotube differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in inflammatory response

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in inflammatory response

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

regulation of cytokine production involved in inflammatory response

Displaying entries **1 - 5** of 18 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	Reference
Golgi membrane	ISS	GO_REF
Golgi membrane	ISO	GO_REF
Golgi membrane	IEA	GO_REF GO_REF
lysosomal membrane
endoplasmic reticulum membrane	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

endomembrane system

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

Displaying **all 5** entries
GO Term	Evidence Code	Reference
D-type glycerophospholipase activity	ISS	PMID
D-type glycerophospholipase activity	TAS	Reactome
D-type glycerophospholipase activity	IDA	PMID
single-stranded DNA 5'-3' DNA exonuclease activity	ISO	GO_REF
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

exonuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' exonuclease activity [inference]

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

lipase activity [inference]

phospholipase activity [inference]

glycerophospholipase activity [inference]

D-type glycerophospholipase activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

D-type glycerophospholipase activity

catalytic activity, acting on a nucleic acid [inference]

nuclease activity [inference]

exonuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' exonuclease activity [inference]

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

DNA nuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

DNA exonuclease activity [inference]

DNA exonuclease activity, producing 5'-phosphomonoesters [inference]

single-stranded DNA exodeoxyribonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

5'-3' DNA exonuclease activity [inference]

single-stranded DNA 5'-3' DNA exonuclease activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKPKLMYQELKVPVEEPAGELPLNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQRPAPCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLQQLQALAPRGVKVRIAVSKPNGPLADLQSLLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRSFDTRYNQETPMEICLNGTPALAYLASAPPPLCPSGRTPDLKALLNVVDSARSFIYIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSDPSMRSFLLSLAALHDNHTHSDIQVKLFVVPTDESQARIPYARVNHNKYMVTERASYIGTSNWSGSYFTETAGTSLLVTQNGHGGLRSQLEAVFLRDWESPYSHDLDTSANSVGNACRLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
97	N-linked (GlcNAc...) asparagine	38537643		UniProt
132	N-linked (GlcNAc...) asparagine			UniProt GlyGen
234	N-linked (GlcNAc...) asparagine	30899004 38537643	G80920RR G74430RZ G06110VR G66538GV G74724QE G14669DU G63628AV	GlycoProtDB UniProt GlyGen GlyConnect
282	N-linked (GlcNAc...) asparagine	30899004	G29015LH G48584BU G14260UH G64527OM G05724UK G39188ZX G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
385	N-linked (GlcNAc...) asparagine	30899004	G85554PZ G70101JE G64527OM G10256JP G05724UK G39188ZX G94854LT G06110VR G66538GV G74724QE G14669DU G31685JQ G22355FZ	GlycoProtDB UniProt GlyGen GlyConnect