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Hyaluronidase-2

Summary

UniProt ID

O35632

Gene Symbol

Hyal2

Gene ID

15587

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003121

GlyConnect

Hyaluronidase-2

GlyGen

O35632

PubChem

O35632

RaftProt

O35632

Re-Glyco

O35632

Annotation

Keyword

Cell membrane
Disulfide bond
EGF-like domain
GPI-anchor
Glycosidase
Receptor
Reference proteome
Signal

Gene Ontology (GO)

Displaying entries **1 - 10** of 13 in total

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GO Term
lysosome
plasma membrane
microvillus
cytoplasmic vesicle
Golgi membrane
cytosol
cell surface
apical plasma membrane
endocytic vesicle
perinuclear region of cytoplasm

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **21 - 30** of 32 in total

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GO Term
viral entry into host cell
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
multicellular organismal-level iron ion homeostasis
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to UV-B
cellular response to transforming growth factor beta stimulus
positive regulation of extrinsic apoptotic signaling pathway
glycosaminoglycan catabolic process
positive regulation of urine volume

Displaying **all 8** entries
GO Term
virus receptor activity
hyalurononglucosaminidase activity
hyaluronic acid binding
enzyme binding
receptor signaling protein tyrosine kinase inhibitor activity
receptor tyrosine kinase binding
hyaluronoglucuronidase activity
transforming growth factor beta binding

Annotation information from UniProt.

Sequence

MRAGLGPIITLALVLEVAWAGELKPTAPPIFTGRPFVVAWNVPTQECAPRHKVPLDLRAFDVKATPNEGFFNQNITTFYYDRLGLYPRFDAAGTSVHGGVPQNGSLCAHLPMLKESVERYIQTQEPGGLAVIDWEEWRPVWVRNWQEKDVYRQSSRQLVASRHPDWPSDRVMKQAQYEFEFAARQFMLNTLRYVKAVRPQHLWGFYLFPDCYNHDYVQNWESYTGRCPDVEVARNDQLAWLWAESTALFPSVYLDETLASSVHSRNFVSFRVREALRVAHTHHANHALPVYVFTRPTYTRGLTGLSQVDLISTIGESAALGSAGVIFWGDSEDASSMETCQYLKNYLTQLLVPYIVNVSWATQYCSWTQCHGHGRCVRRNPSANTFLHLNASSFRLVPGHTPSEPQLRPEGQLSEADLNYLQKHFRCQCYLGWGGEQCQRNYKGAAGNASRAWAGSHLTSLLGLVAVALTWTL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
74	N-linked (GlcNAc...) asparagine	19349973	G39446WN	GlycoProtDB UniProt GlyGen
103	N-linked (GlcNAc...) asparagine		G41247ZX	GlycoProtDB UniProt GlyGen
357	N-linked (GlcNAc...) asparagine			UniProt GlyGen
390	N-linked (GlcNAc...) asparagine	19349973	G39188ZX G41247ZX	GlycoProtDB UniProt GlyGen GlyConnect
448	N-linked (GlcNAc...) asparagine; alternate		G41071NU	UniProt GlyGen