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Latent-transforming growth factor beta-binding protein 2

Summary

UniProt ID: O35806
Gene Symbol: Ltbp2
Gene ID: 59106
Organism: Rattus norvegicus (Norway rat)

External Links

Re-Glyco: O35806

Annotation

Keyword: Disulfide bond EGF-like domain Extracellular matrix Glycoprotein Growth factor binding Heparin-binding Hydroxylation Phosphoprotein Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
transforming growth factor beta receptor signaling pathway	NAS	PMID
response to alkaloid	IEP	PMID
supramolecular fiber organization	ISO	GO_REF
supramolecular fiber organization	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

supramolecular fiber organization

response to stimulus [inference]

response to chemical [inference]

response to nitrogen compound [inference]

response to alkaloid

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	Reference
calcium ion binding	IEA	GO_REF
heparin binding
growth factor binding
microfibril binding	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

growth factor binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

extracellular matrix binding [inference]

microfibril binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRAPTTVRCSGRIQRARWRGFLPLVLALLMGTSHAQRDSVGRYEPASRDANRLWRPVGNHPAAAAAKVYSLFREPDAPVPGLSPSEWNQPGQGIPGRLAEAEARRPSRAQQLRRVQSPVQTRRSNPRGQQPPAARTAHSVVRLATPQRPAAARRGRLTGRNVCGGQCCPGWTTSNSTNHCIKPVCQPPCQNRGSCSRPQLCICRSGFRGARCEEVIPEEEFDPQNARPVPRRSVEGAPGPHRSSEARGSLVTRIQPLLPPLPPPPSRTLSQTRPLQQHAGLSRTVRRYPATGTNGQLMSNALPSGPGPELRDSSQQAAHMNHLSHPWGLNLTEKIKKIKVVFTPTICKQTCARGRCANTCEKGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRCIGRDECWCPANSTGKFCHLPVPQPDREPPGRGSQHRALLEGPLKQSTFTLPLSNQLASVNPSLVKVQMQHPPEASVQIHQVARVRGEVDPVPEDNSVETRASHRPHGSSGHSHWASNSIPARAGEAPRPPPVPSRHYGLLGQCYLSTVNGQCANPLGELTSQEDCCGSVGTSWGVTSCAPCPPRPAFPVIENGQLECPQGYKRLNLSHCQDINECLTLGLCKDSECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAVSMKQGLCYRSMVSGTCTLPLVQRITKQICCCSRVGKAWGSKCEHCPLPGTEAFREICPAGHGYAYSSSDIRLSMRKAEEEELASPVREQRQQSSGPPPGAAERQPLRAATATWIEAETLPDKGDSRAIQITTSAPHLPARVPGDATGRPTPSLPGQGIPEGPAEEQVIPSSDVLVTHGPPGFDPCFAGASNICGPGTCVKLPNGYRCVCSPGYQLHPSQDYCTDDNECLRNPCEGRGRCVNSVGSYSCLCYPGYTLATLGDTQECQDVDECEQPGVCSGGRCSNTEGSYHCECDQGYVMVRRGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYIGQSGNCVDMNECLTPGICAHGRCINMEGSFRCSCEPGYELTPDKKGCRDVDECASRASCPTGLCLNTEGSFTCSACQSGYWVNEDGTACEDLDECAFPGVCPTGVCTNTVGSFSCKDCDRGFRPSPLGNSCEDVDECEGPQNSCLGGECKNTDGSYQCLCPQGFQLANGTVCEDVDECVGEEHCAPHGECLNSPGSFFCLCAPGFASAEGGTRCQDVDECATTEPCLGGHCVNTEGSFNCLCETGFQPAPDSGECVDIDECANDTVCGNHGFCDNTDGSFRCLCDQGFETSPSGWECVDVNECELMLAVCGDALCENVEGSFLCLCASDLEEYDAEEGHCRPRVAGAQRIPEVPTEEQAAGLTGMECYAEHNGGPPCSQILGQNSTQAECCSTQGARWGETCDPCPSEDSVEFSELCPSGQGYIPVEGAWTFGQAMYTDADECILFGPALCQNGRCLNTVPGYICLCNPGYHYDAVSRKCQDHNECQDLACENGECVNTEGSFHCFCSPPLILDLSGQRCVNSTSSSEDFPDHDIHMDICWKKVTNDVCSQPLRGHHTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGIHFRPGYEYGPGPDDLPETLYGPDGAPFYNYLGPEDTVPEPPFSNTASHLGDNTPILEPPLQPSELQPPAIQNPLASFEGLQAEECGILNGCENGRCVRVREGYTCDCFEGFQLDTALMACVDVNECEDLNGAARLCAHGHCENTEGSYRCHCSPGYVAEPGPPHCAAKE

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	Source
175	N-linked (GlcNAc...) asparagine	UniProt
330	N-linked (GlcNAc...) asparagine	UniProt
408	N-linked (GlcNAc...) asparagine	UniProt
602	N-linked (GlcNAc...) asparagine	UniProt
1160	N-linked (GlcNAc...) asparagine	UniProt
1255	N-linked (GlcNAc...) asparagine	UniProt
1376	N-linked (GlcNAc...) asparagine	UniProt
1514	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Molecules associated with elastic fibres	Rattus norvegicus
TGF-beta receptor signaling activates SMADs	Rattus norvegicus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

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International Collaboration

Acknowledgements