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Frizzled-3

Summary

UniProt ID: O42579
Gene Symbol: fzd3 fz3
Gene ID: 399190
Organism: Xenopus laevis (African clawed frog)

External Links

Re-Glyco: O42579

Annotation

Keyword: Cell membrane Developmental protein Disulfide bond G-protein coupled receptor Glycoprotein Neurogenesis Reference proteome Signal Transmembrane helix Wnt signaling pathway

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
nervous system development
neural crest cell fate specification	TAS	PMID
regulation of protein localization	IDA	PMID
non-canonical Wnt signaling pathway	IBA	GO_REF
non-canonical Wnt signaling pathway	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

cellular developmental process [inference]

cell fate specification [inference]

stem cell fate specification [inference]

neural crest cell fate specification

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell fate specification [inference]

stem cell fate specification [inference]

neural crest cell fate specification

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

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GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF
cell surface	ISS	GO_REF
cell surface	IEA	GO_REF
apical plasma membrane	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

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GO Term	Evidence Code	Reference
protein serine/threonine kinase activity	IMP	PMID
G protein-coupled receptor activity
Wnt-protein binding	IBA	GO_REF
Wnt-protein binding	IEA	GO_REF
Wnt receptor activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

binding [inference]

protein binding [inference]

Wnt-protein binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAAYLISFIWVSVILAQKSMGHSLFACEPITLRMCQDLPYNSTFMPNLLNHYDQQTAALAMEPFHPMVNLECSRDLRPFLCALYTPVCMEYGRMTLPCRKLCQRAYNECFKLMEMFGVPWPEEMECSRFPDCDEPYPRIVDISLSGEPSEETPLAVQRDYGFWCPRELKIDPDLRSSFLGVRDCSPPCPHMYFRREELSFARYFIGVISIVCLSATLFTFLTFLIDVTRFRYPERPIIFYAVCYMMVSLIFFIGFLLEDKVACNGANPSQYKASTVTQGSHNKACTMLFMVLYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVHALRYFVLAPLCLDVVVGVSLLLAGIISLNRVRIEIPLEKENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYRGVWETTWVQERCREYHIPCPYKVTQTSRPDLILFLMKYLMLLVVGIPSVFWVGSKKTCFEWASFFHGRKKKAGVNESRQVLQEPDFAQSLLRDPNTPIVRKSRGTSTQGTSTHASSTQLAMLDDQRSKAGSVQSKVSSYHGSLHRSRDGRYTPCSYRGIEERLPHGSMSHLTDHSRHSSTHRLNEQSHQGSIRDLSNPLAHISHGTSMNRVIEADATSA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites