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MIRAGE
Protein-glutamine gamma-glutamyltransferase 5

Summary
UniProt ID
O43548
Gene Symbol
  • TGM5
  • TGMX
Gene ID
9333
Organism
Homo sapiens (human)
GlyGen
O43548
PubChem
O43548
The Human Metabolome Database
HMDBP00679
The O-GlcNAc Database
O43548
O-GlcNAcAtlas
O43548
Re-Glyco
O43548
Annotation
Keyword
  • Acetylation
  • Acyltransferase
  • Alternative splicing
  • Calcium
  • Cytoplasm
  • Direct protein sequencing
  • Disease variant
  • Metal-binding
  • Reference proteome
Gene Ontology (GO)
Displaying all 2 entries
GO Term
cytoplasm
plasma membrane
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
epidermis development
protein modification process
Annotation information from UniProt.
Sequence
MAQGLEVALTDLQSSRNNVRHHTEEITVDHLLVRRGQAFNLTLYFRNRSFQPGLDNIIFVVETGPLPDLALGTRAVFSLARHHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIHIDSFQGSVTAYQLGEFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPAYGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQGGKEQKLHQDTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFKDLKVNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALGEEKSSPEKILVNKIITLSYPSITINVLGAAVVNQPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
493
498
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Formation of the cornified envelope Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0070521 peeling skin syndrome 2
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025