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Nuclear factor erythroid 2-related factor 2

Summary

UniProt ID

O54968

Gene Symbol

Nfe2l2
Nrf2

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: O54968

Annotation

Keyword

Acetylation
Activator
Alternative splicing
Cytoplasm
DNA-binding
Glycation
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

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GO Term
inflammatory response
response to oxidative stress
response to organic substance
aflatoxin catabolic process
regulation of DNA-templated transcription
regulation of transcription by RNA polymerase II
response to xenobiotic stimulus
positive regulation of DNA-templated transcription
positive regulation of transcription by RNA polymerase II
positive regulation of glucose import

Displaying **all 10** entries
GO Term
cytosol
nucleoplasm
centrosome
protein-DNA complex
RNA polymerase II transcription regulator complex
nucleus
cytoplasm
Golgi apparatus
plasma membrane
chromatin

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GO Term
DNA binding
RNA polymerase II-specific DNA-binding transcription factor binding
protein domain specific binding
ubiquitin protein ligase binding
transcription cis-regulatory region binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA-binding transcription factor activity
sequence-specific DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MMDLELPPPGLQSQQDMDLIDILWRQDIDLGVSREVFDFSQRQKDYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQTDTSGSVSYSQVAHIPKQDALYFEDCMQLLAETFPFVDDHEVSSPTFQSLALDIPSHVESSVFTTPDQAQSLDSSLETAMTDLSSIQQDMEQVWQELFSIPELQCLNTENKQQAETTTVPSPEATLTEMDSNYHFYSSIPSLEKEVDSCSPHFLHGFEDSFSSILSTDDASQLNSLDSNPTLNTDFGDEFYSAFLAEPSGGGSMPSSAAISQSLSELLGGPIEGCDLSLCKAFNQKHTEGTVEFNDSDSGISLNTSPSRASPEHSVESSIYGDPPPGFSDSEMEELDSAPGSVKQNGPKAQPTHSSGDTVQPLSPAQGHSAAVHESQCENTTKKEVPVSPGHQKVPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVDDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRKLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDTKKN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
461	N-linked (Glc) (glycation) lysine	UniProt
471	N-linked (Glc) (glycation) lysine	UniProt
486	N-linked (Glc) (glycation) lysine	UniProt
498	N-linked (Glc) (glycation) arginine	UniProt
568	N-linked (Glc) (glycation) arginine	UniProt
573	N-linked (Glc) (glycation) lysine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	Rattus norvegicus
KEAP1-NFE2L2 pathway	Rattus norvegicus
Neddylation	Rattus norvegicus
Nuclear events mediated by NFE2L2	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements