Matrix metalloproteinase-20

Summary
UniProt ID
O60882
Gene Symbol
  • MMP20
Gene ID
9313
Organism
Homo sapiens (human)
PubChem
O60882
The Human Metabolome Database
HMDBP02615
The O-GlcNAc Database
O60882
Re-Glyco
O60882
Annotation
Keyword
  • 3D-structure
  • Amelogenesis imperfecta
  • Autocatalytic cleavage
  • Calcium
  • Disulfide bond
  • Extracellular matrix
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Repeat
  • Signal
  • Zinc
  • Zymogen
Gene Ontology (GO)
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
zinc ion binding
metalloendopeptidase activity
Sequence
MKVLPASGLAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
67
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 3 entries
Pathway Name Organism
Assembly of collagen fibrils and other multimeric structures Homo sapiens
Collagen degradation Homo sapiens
Degradation of the extracellular matrix Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0110060 amelogenesis imperfecta hypomaturation type 2A2

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025