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Myosin-binding protein C, cardiac-type

Summary

UniProt ID: O70468
Gene Symbol: Mybpc3
Gene ID
Organism: Mus musculus (house mouse)

External Links

GlyGen: O70468
The O-GlcNAc Database: O70468
Re-Glyco: O70468

Annotation

Keyword: 3D-structure Acetylation Actin-binding Cell adhesion Disulfide bond Immunoglobulin domain Metal-binding Methylation Phosphoprotein Reference proteome Repeat Thick filament Ubl conjugation Zinc

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
regulation of heart rate	IMP	PMID
heart morphogenesis	ISO	GO_REF
heart morphogenesis	IMP	PMID PMID
muscle contraction	TAS	PMID
cell adhesion

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

sarcomere organization

myosin filament organization [inference]

myosin filament assembly

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

sarcomere organization

myosin filament organization [inference]

myosin filament assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

myosin filament assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

myosin filament assembly

supramolecular fiber organization [inference]

myosin filament organization [inference]

myosin filament assembly

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction

striated muscle contraction [inference]

cardiac muscle contraction

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

heart morphogenesis

tissue morphogenesis [inference]

muscle tissue morphogenesis [inference]

cardiac muscle tissue morphogenesis [inference]

ventricular cardiac muscle tissue morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction

regulation of heart rate

regulation of biological quality [inference]

regulation of heart rate

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GO Term	Evidence Code	Reference
cytoskeleton	TAS	PMID
striated muscle myosin thick filament	ISO	GO_REF GO_REF
myofibril	IDA	PMID
sarcomere	ISO	GO_REF
sarcomere	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

myofilament [inference]

striated muscle myosin thick filament

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

contractile muscle fiber [inference]

myofibril

cardiac myofibril

intracellular organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

contractile muscle fiber [inference]

myofibril

cardiac myofibril

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

myosin filament [inference]

striated muscle myosin thick filament

contractile muscle fiber [inference]

myofibril

cardiac myofibril

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
actin binding
structural constituent of cytoskeleton	TAS	PMID
structural constituent of muscle	ISO	GO_REF
structural constituent of muscle	IBA	GO_REF
myosin binding	ISO	GO_REF

GO Hierarchy

molecular function

structural molecule activity [inference]

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

actin binding

myosin binding

myosin heavy chain binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MPEPGKKPVSAFNKKPRSAEVTAGSAAVFEAETERSGVMVRWQRDGSDITANDKYGLAAEGKRHTLTVRDASPDDQGSYAVIAGSSKVKFDLKVTEPAPPEKAESEVAPGAPEEVPAPATELEESVSSPEGSVSVTQDGSAAEHQGAPDDPIGLFLMRPQDGEVTVGGSIVFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQHLQLHDSYDRASKVYLFELHITDAQTTSAGGYRCEVSTKDKFDSCNFNLTVHEAIGSGDLDLRSAFRRTSLAGAGRRTSDSHEDAGTPDFSSLLKKRDSFRRDSKLEAPAEEDVWEILRQAPPSEYERIAFQHGVEACHRPLKRLKGMKQDEKKSTAFQKKLEPAYQVNKGHKIRLTVELADPDAEVKWLKNGQEIQMSGSKYIFESVGAKRTLTISQCSLADDAAYQCVVGGEKCSTELFVKEPPVLITRSLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFKKDGRKHHLIINEATLEDAGHYAVRTSGGQSLAELIVQEKKLEVYQSIADLAVGAKDQAVFKCEVSDENVRGVWLKNGKELVPDNRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGSTPDTIVVVTGNKLRLDVPISGDPAPTVVWQKTVTQGKKASAGPHPDAPEDAGADEEWVFDKKLLCETEGRVRVETTKDRSVFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPVLGYILERKKKKSYRWMRLNFDLLRELSHEARRMIEGVAYEMRVYAVNAVGMSRPSPASQPFMPIGPPGEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCQEGCSEWTPALQGLTERRSMLVKDLPTGARLLFRVRAHNVAGPGGPIVTKEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRTHSGTYQVTVRIENMEDKATLILQIVDKPSPPQDIRIVETWGFNVALEWKPPQDDGNTEIWGYTVQKADKKTMEWFTVLEHYRRTHCVVSELIIGNGYYFRVFSHNMVGSSDKAAATKEPVFIPRPGITYEPPKYKALDFSEAPSFTQPLANRSIIAGYNAILCCAVRGSPKPKISWFKNGLDLGEDARFRMFCKQGVLTLEIRKPCPYDGGVYVCRATNLQGEAQCECRLEVRVPQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
676				GlyGen
954		34418053 36288343	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Striated Muscle Contraction	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110310	hypertrophic cardiomyopathy 4	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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External Links

Annotation

International Collaboration

Acknowledgements