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Integrin alpha-10

Summary

UniProt ID: O75578
Gene Symbol: ITGA10 UNQ468/PRO827
Gene ID: 8515
Organism: Homo sapiens (human)

External Links

PubChem: O75578
Re-Glyco: O75578

Annotation

Keyword: Alternative splicing Calcium Cell adhesion Disulfide bond Glycoprotein Integrin Magnesium Metal-binding Proteomics identification Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
cell-matrix adhesion	NAS	PMID
cell-matrix adhesion	TAS	PMID
cell-matrix adhesion	IMP	PMID
integrin-mediated signaling pathway	NAS	PMID
integrin-mediated signaling pathway	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
plasma membrane	TAS	Reactome Reactome Reactome Reactome Reactome Reactome
integrin complex	TAS	PMID
integrin complex	IEA	GO_REF GO_REF
cell surface	IBA	GO_REF
integrin alpha10-beta1 complex	IDA	PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alpha10-beta1 complex

protein complex involved in cell adhesion [inference]

integrin complex

integrin alpha10-beta1 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alpha10-beta1 complex

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	Reference
collagen binding	TAS	PMID
signaling receptor activity	IBA	GO_REF
metal ion binding
collagen binding involved in cell-matrix adhesion	IMP	PMID
collagen binding involved in cell-matrix adhesion	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

cell-matrix adhesion mediator activity [inference]

collagen binding involved in cell-matrix adhesion

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

collagen binding

collagen binding involved in cell-matrix adhesion

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MELPFVTHLFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREEKLEQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 11 in total

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Position	Description	Source
98	N-linked (GlcNAc...) asparagine	UniProt
234	N-linked (GlcNAc...) asparagine	UniProt
336	N-linked (GlcNAc...) asparagine	UniProt
364	N-linked (GlcNAc...) asparagine	UniProt
733	N-linked (GlcNAc...) asparagine	UniProt
763	N-linked (GlcNAc...) asparagine	UniProt
839	N-linked (GlcNAc...) asparagine	UniProt
921	N-linked (GlcNAc...) asparagine	UniProt
1011	N-linked (GlcNAc...) asparagine	UniProt
1018	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
CHL1 interactions	Homo sapiens
Integrin cell surface interactions	Homo sapiens
Platelet Adhesion to exposed collagen	Homo sapiens

GlyTouCan

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UniCarb-DR

LM-GlycoRepo

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