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Sodium-dependent acetylcholine transporter

Summary

UniProt ID: O76689
Gene Symbol: snf-6 M01G5.5
Gene ID: 191768
Organism: Caenorhabditis elegans

External Links

PubChem: O76689
Re-Glyco: O76689

Annotation

Keyword: Cell membrane Glycoprotein Neurotransmitter transport Postsynaptic cell membrane Reference proteome Symport Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
neurotransmitter uptake	NAS	PMID
neuromuscular synaptic transmission	NAS	PMID
acetylcholine transport	IDA	PMID
choline transport	IDA	PMID
sodium ion transmembrane transport	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

neuromuscular synaptic transmission

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

carboxylic acid transmembrane transport [inference]

glycine import across plasma membrane

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

neurotransmitter transport [inference]

neurotransmitter uptake

amino acid transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

neutral amino acid transport [inference]

glycine transport [inference]

glycine import across plasma membrane

organic cation transport [inference]

glycine transport [inference]

glycine import across plasma membrane

organic anion transport [inference]

carboxylic acid transport [inference]

glycine transport [inference]

glycine import across plasma membrane

carboxylic acid transmembrane transport [inference]

glycine import across plasma membrane

organic acid transport [inference]

carboxylic acid transport [inference]

glycine transport [inference]

glycine import across plasma membrane

carboxylic acid transmembrane transport [inference]

glycine import across plasma membrane

transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

carboxylic acid transmembrane transport [inference]

glycine import across plasma membrane

nitrogen compound transport [inference]

glycine transport [inference]

glycine import across plasma membrane

import into cell [inference]

neurotransmitter uptake

import across plasma membrane [inference]

amino acid import across plasma membrane [inference]

glycine import across plasma membrane

acetate ester transport [inference]

acetylcholine transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

neuromuscular synaptic transmission

regulation of locomotion [inference]

positive regulation of locomotion

positive regulation of biological process [inference]

positive regulation of locomotion

Displaying **all 4** entries
GO Term	Evidence Code	Reference
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
postsynaptic membrane	NAS	PMID
postsynaptic membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

Displaying **all 5** entries
GO Term	Evidence Code	Reference
acetylcholine transmembrane transporter activity	IDA	PMID
amino acid:sodium symporter activity	IBA	GO_REF
neurotransmitter:sodium symporter activity	NAS	PMID
L-amino acid transmembrane transporter activity	IBA	GO_REF
PDZ domain binding	IPI	PMID

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

neurotransmitter transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:sodium symporter activity

solute:sodium symporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

amino acid transmembrane transporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:sodium symporter activity

L-amino acid transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

amino acid:monoatomic cation symporter activity [inference]

amino acid:sodium symporter activity

solute:sodium symporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

L-amino acid transmembrane transporter activity

acetate ester transmembrane transporter activity [inference]

acetylcholine transmembrane transporter activity

binding [inference]

protein binding [inference]

protein domain specific binding [inference]

PDZ domain binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSVSSNDPEQRNGRGMASGNNVDMSLYPPFIKQLDAKLPDYTREGDIEYPFEEITGVGDENRIRGNWSNKSDYLLAVIGFTAGVGSFWKFPFLVFQHGGAAFLVPYLCMLCLASLPMFFMEMVLGQFSSSAAISVWKVVPLFKGIGFAQVTISGFFAVFFNIISAWTLFYLINSFSFSIPWSNCANSWSGENCTLGTRIQCKEMNGTLLVNGSCIVEHASSNETTVIPLHDLGSIPSLKYFHNDVLMLSKGVDDFGTLNWYLGLCVLACWIAVFLCLFQGVKSSGKVVYVAVIVPFIILTVLLTRLLTLDGSLAAVFYFLTPKWEILMDLHVWGEAAVQAFYSVSCCSGGLFTIASYSRFHNNIYKDIWLVLIVDVIVSLVGCLLTFSAIGFTCYEFAISLDKFHIRDGFHLVFVFLAEALAGVSVAPLYAGLFFIMILLVVHATQMFVVETIVSSICDEYPERLRRNRRHVLTTVCALFILLSIPFCLSSGLFWMELLTQFVLTWPLVVIAFLECMAINWVYGVDNMLDNAKWIVGYWPPCYIFWKILFKFICPMVYLAILCFLWLDWNSIQYESYQFPYWSILTAWCIASFPLILIPIVGIWQFCIAKGTITQKWWRVLYPDDAWGPAMAIHRAEKFPLQIPEARRLLLPPEVEIASSRGVLQEEMPMSYDYNTSSAADVRSNRSTGHGATDVRSVAATNNTIPKFERETAI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
192	N-linked (GlcNAc...) asparagine	UniProt
205	N-linked (GlcNAc...) asparagine	UniProt
211	N-linked (GlcNAc...) asparagine	UniProt
222	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Amino acid transport across the plasma membrane	Caenorhabditis elegans
SLC-mediated transport of neurotransmitters	Caenorhabditis elegans

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:11723	Duchenne muscular dystrophy	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements