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Ciliary neurotrophic factor receptor subunit alpha

Summary

UniProt ID: O88507
Gene Symbol: Cntfr
Gene ID: 12804
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003209

GlyConnect

Ciliary neurotrophic factor receptor subunit alpha

GlyGen

O88507

PubChem

O88507

Re-Glyco

O88507

Annotation

Keyword: Cell membrane Disulfide bond GPI-anchor Immunoglobulin domain Receptor Reference proteome Repeat Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
suckling behavior	IMP	PMID
brainstem development	IMP	PMID
sex differentiation	IMP	PMID
positive regulation of cell population proliferation	IGI	PMID
positive regulation of cell population proliferation	IBA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

ciliary neurotrophic factor-mediated signaling pathway

reproductive process [inference]

developmental process involved in reproduction [inference]

sex differentiation

multicellular organismal process [inference]

behavior [inference]

feeding behavior [inference]

suckling behavior

developmental process [inference]

developmental process involved in reproduction [inference]

sex differentiation

anatomical structure development [inference]

brainstem development

animal organ development [inference]

muscle organ development [inference]

skeletal muscle organ development

muscle structure development [inference]

muscle organ development [inference]

skeletal muscle organ development

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway [inference]

ciliary neurotrophic factor-mediated signaling pathway

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

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GO Term	Evidence Code	Reference
external side of plasma membrane	ISS	GO_REF
external side of plasma membrane	ISO	GO_REF
external side of plasma membrane	IBA	GO_REF
external side of plasma membrane	IEA	GO_REF
apical plasma membrane	ISO	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

ciliary neurotrophic factor receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

ciliary neurotrophic factor receptor complex

extracellular protein-containing complex [inference]

CNTFR-CLCF1 complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
ciliary neurotrophic factor receptor activity	ISS	GO_REF
ciliary neurotrophic factor receptor activity	ISO	GO_REF GO_REF
ciliary neurotrophic factor receptor activity	IGI	PMID
ciliary neurotrophic factor receptor activity	IEA	GO_REF GO_REF
interleukin-11 receptor activity	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

growth factor binding [inference]

interleukin-11 binding

cytokine binding

interleukin-11 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity [inference]

immune receptor activity [inference]

cytokine receptor activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAASVPWACCAVLAAAAAAVYTQKHSPQEAPHVQYERLGADVTLPCGTASWDAAVTWRVNGTDLAPDLLNGSQLILRSLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNTTAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLTTEAQAPETTTSTTSSLAPPPTTKICDPGELGSGGGPSILFLTSVPVTLVLAAAAATANNLLI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
60	N-linked (GlcNAc...) asparagine	19349973	G63703BK	GlycoProtDB UniProt GlyGen
70	N-linked (GlcNAc...) asparagine	19349973	G47370JY	GlycoProtDB UniProt GlyGen
142	N-linked (GlcNAc...) asparagine	30899004	G06156DS G70418MS G23863VK G82119TF G29880MM G06110VR	UniProt GlyGen GlyConnect
190	N-linked (GlcNAc...) asparagine	30899004	G06110VR G92050GC	UniProt GlyGen GlyConnect