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Sodium/nucleoside cotransporter 2

Summary

UniProt ID: O88627
Gene Symbol: Cnt2 Slc28a2
Gene ID: 269346
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003219
PubChem: O88627
Re-Glyco: O88627

Annotation

Keyword: Cell membrane Phosphoprotein Reference proteome Transmembrane helix Transport

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
retina homeostasis	IBA	GO_REF
neurotransmitter transport	ISO	GO_REF
purine nucleoside transmembrane transport	ISO	GO_REF
purine nucleoside transmembrane transport	TAS	PMID
uridine transmembrane transport	ISO	GO_REF

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

purine-containing compound transmembrane transport [inference]

pyrimidine-containing compound transmembrane transport

uridine transmembrane transport

nucleoside transmembrane transport

multicellular organismal process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

retina homeostasis

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

retina homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

neurotransmitter transport

transmembrane transport [inference]

purine-containing compound transmembrane transport [inference]

pyrimidine-containing compound transmembrane transport

uridine transmembrane transport

nucleoside transmembrane transport

nitrogen compound transport [inference]

nucleobase transport [inference]

purine nucleobase transport [inference]

purine nucleobase transmembrane transport

nucleobase-containing compound transport [inference]

nucleoside transport [inference]

pyrimidine nucleoside transport [inference]

uridine transmembrane transport

nucleoside transmembrane transport

purine-containing compound transmembrane transport [inference]

pyrimidine-containing compound transmembrane transport

uridine transmembrane transport

carbohydrate derivative transport [inference]

nucleoside transport [inference]

pyrimidine nucleoside transport [inference]

uridine transmembrane transport

nucleoside transmembrane transport

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
plasma membrane	ISS	PMID
plasma membrane	ISO	GO_REF
plasma membrane	IBA	GO_REF
vesicle membrane	ISO	GO_REF
apicolateral plasma membrane	ISS	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane

plasma membrane region [inference]

apicolateral plasma membrane

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	Reference
neurotransmitter transmembrane transporter activity	ISO	GO_REF
nucleoside transmembrane transporter activity	ISO	GO_REF
nucleoside transmembrane transporter activity	IEA	GO_REF
purine nucleobase transmembrane transporter activity	ISO	GO_REF
nucleoside:sodium symporter activity	ISO	GO_REF GO_REF

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

neurotransmitter transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase:monoatomic cation symporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase transmembrane transporter activity [inference]

purine nucleobase transmembrane transporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

pyrimidine nucleobase transmembrane transporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase:monoatomic cation symporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase-containing compound transmembrane transporter activity [inference]

nucleoside transmembrane transporter activity

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

purine nucleoside transmembrane transporter activity

pyrimidine nucleoside transmembrane transporter activity [inference]

uridine transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

nucleobase:monoatomic cation symporter activity [inference]

pyrimidine- and adenosine-specific:sodium symporter activity

carbohydrate derivative transmembrane transporter activity [inference]

nucleoside transmembrane transporter activity

nucleoside:sodium symporter activity

pyrimidine- and adenosine-specific:sodium symporter activity

purine nucleoside transmembrane transporter activity

pyrimidine nucleoside transmembrane transporter activity [inference]

uridine transmembrane transporter activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MEKSKGRKSVSQATVENCMENPGLELMEGGNLEQRYTQEEVTQGHSLEDGLGHSSLWSRRIFQPFTKARSFFERHAGLFRKILLGLLCLAYAAYFLAACILNFQRALALFVITCLVIFILACHFLKKFFPKEQLRCLKPLENTHLNLWAKRVFVGLSVVGLILWLALDTAQRPEQLISFAGICMFILILFACSKHHSAVCWRTVFWGLGLQFIFGILVIRTEPGFNAFQWLGDQIQIFLAYTVEGSSFVFGDTLVQNVFAFQSLPIIIFFGCVMSILYYLGLVQWVIQKVAWFLQITMGTTAAETLAVAGNIFVGMTEAPLLIRPYLADMTISEIHAVMTGGFATIAGTVLGAFISFGIDASSLISASVMAAPCALALSKLVYPEVEESKFKSKEGLKLPRGEERNILEAASNGATDAISLVANVAANLIAFLAVLAFINATLSWLGEMVDIHGLSFQVICSYVLRPMVFMMGVQWADCPLVAEIVGVKFFINEFVAYQQLSQYKNKRLSGVEEWINGEKQWISVKAEIITTFSLCGFANLSSIGITLGGLTSMIPQRKSDLCKIVVRALFTGACVSFISACMAGILYVPRGAETDCVSFLNTNFTNRTYETYVCCRELFQSTSLNGTNMPSFSGPWQDNVSSLRNLASCCDLYTSTVCA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
604				GlycoProtDB
607				GlycoProtDB
626				GlycoProtDB
640				GlycoProtDB

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Azathioprine ADME	Mus musculus
Ribavirin ADME	Mus musculus
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

International Collaboration

Acknowledgements