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MIRAGE
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Summary
- UniProt ID
- O88704
- Gene Symbol
- Bcng1 Hac2 Hcn1
- Gene ID
- 15165
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- 3D-structure Cell membrane Glycoprotein Ligand-gated ion channel Potassium channel Reference proteome Sodium channel Transmembrane helix Voltage-gated channel cAMP-binding
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| regulation of membrane depolarization | ||
| regulation of membrane depolarization | ||
| regulation of membrane depolarization | ||
| neuronal action potential | ||
| cellular response to interferon-beta |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| intracellularly cAMP-activated cation channel activity | ||
| intracellularly cAMP-activated cation channel activity | ||
| intracellularly cAMP-activated cation channel activity | ||
| voltage-gated sodium channel activity | ||
| voltage-gated sodium channel activity |
GO Hierarchy
Sequence
MEGGGKPNSASNSRDDGNSVFPSKAPATGPVAADKRLGTPPGGGAAGKEHGNSVCFKVDGGGGEEPAGSFEDAEGPRRQYGFMQRQFTSMLQPGVNKFSLRMFGSQKAVEKEQERVKTAGFWIIHPYSDFRFYWDLIMLIMMVGNLVIIPVGITFFTEQTTTPWIIFNVASDTVFLLDLIMNFRTGTVNEDSSEIILDPKVIKMNYLKSWFVVDFISSIPVDYIFLIVEKGMDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQDFPPDCWVSLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRYQGKIFDEENILSELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQKDLNTGVFNNQENEILKQIVKHDREMVQAIPPINYPQMTALNCTSSTTTPTSRMRTQSPPVYTATSLSHSNLHSPSPSTQTPQPSAILSPCSYTTAVCSPPIQSPLATRTFHYASPTASQLSLMQQPQQQLPQSQVQQTQTQTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQTPGSSTPKNEVHKSTQALHNTNLTKEVRPLSASQPSLPHEVSTLISRPHPTVGESLASIPQPVAAVHSTGLQAGSRSTVPQRVTLFRQMSSGAIPPNRGVPPAPPPPAAVQRESPSVLNTDPDAEKPRFASNL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 327 |
|
|
||
| 634 |
|
|||
| 637 |
|
|||
| 639 |
|
|||
| 640 |
|
|||
| 641 |
|
|||
| 642 |
|
|||
| 643 |
|
|||
| 644 |
|
|||
| 792 |
|
G49108TO
G10486CT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| HCN channels | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:13884 | sick sinus syndrome |
