GlyCosmos Portal

Annotation

Keyword: Alternative splicing Chromatin regulator Chromosome Coiled coil Cytoplasm Isopeptide bond Metal-binding Methylation Methyltransferase Nucleus Phosphoprotein Reference proteome Repeat Repressor S-adenosyl-L-methionine Transcription regulation Ubl conjugation Zinc

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	Reference
negative regulation of transcription by RNA polymerase II	IMP	PMID
inner cell mass cell proliferation	IMP	PMID
DNA methylation-dependent constitutive heterochromatin formation	ISS	GO_REF
DNA methylation-dependent constitutive heterochromatin formation	ISO	GO_REF
DNA methylation-dependent constitutive heterochromatin formation	IMP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

methylation

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cell population proliferation [inference]

inner cell mass cell proliferation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

heterochromatin organization

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

cellular component assembly [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

bone development

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of viral process [inference]

negative regulation of viral genome replication [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

regulation of viral process [inference]

negative regulation of viral process [inference]

negative regulation of viral genome replication [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

regulation of viral life cycle [inference]

regulation of viral genome replication [inference]

negative regulation of viral genome replication [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

regulation of single stranded viral RNA replication via double stranded DNA intermediate [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of single stranded viral RNA replication via double stranded DNA intermediate [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

epigenetic regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of single stranded viral RNA replication via double stranded DNA intermediate [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of single stranded viral RNA replication via double stranded DNA intermediate [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of single stranded viral RNA replication via double stranded DNA intermediate [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

transposable element silencing [inference]

transposable element silencing by heterochromatin formation

negative regulation of gene expression, epigenetic [inference]

heterochromatin formation [inference]

constitutive heterochromatin formation [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
chromatin	ISS	GO_REF
chromatin	ISO	GO_REF
nucleus	ISO	GO_REF
nucleus	EXP	PMID
nucleus	IDA	PMID

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	Reference
DNA binding	IDA	PMID
DNA binding	IEA	GO_REF GO_REF
chromatin binding	ISO	GO_REF
chromatin binding	IDA	PMID
zinc ion binding	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H3K9 methyltransferase activity

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H3K9 methyltransferase activity

histone methyltransferase activity [inference]

histone H3 methyltransferase activity [inference]

histone H3K9 methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

lysine N-methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H3K9 methyltransferase activity

catalytic activity, acting on a protein [inference]

protein methyltransferase activity [inference]

protein-lysine N-methyltransferase activity [inference]

histone H3K9 methyltransferase activity

histone methyltransferase activity [inference]

histone H3 methyltransferase activity [inference]

histone H3K9 methyltransferase activity

histone modifying activity [inference]

histone methyltransferase activity [inference]

histone H3 methyltransferase activity [inference]

histone H3K9 methyltransferase activity

binding [inference]

nucleic acid binding [inference]

DNA binding

chromatin binding

promoter-specific chromatin binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

chromatin-protein adaptor activity [inference]

histone reader activity [inference]

histone H3 reader activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MSSLPGCMSLAAAPAAADSAEIAELQQAVVEELGISMEELRQYIDEELEKMDCIQQRKKQLAELETWVLQKESEVAYVDRLFDDASREVTNCESLVKDFYSKLGLQYHDSSSEDEASRPTEIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLFVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQDLTGTGIQFKPMEPLQPIAPPAPLPIPPLSPQAADTDLESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSSTLSENVSAGKLGINQTYRSPLASVTSTPASAAPPVPPVPPGPPTPPGPPAPPGPLAPPAFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRIRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPNSGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDVPTSSDSSGVDMKDQEDGNSGSEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENELSEMTSKDSRPPDLGPPHVPIPSSVSVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSRSSFKTSEGGDGRAGGGRGEAERASTSGLSFKDEGDNKQPKKEDPENRNKMPVVTEGSQNHGHNPPMKSEGLRRPASKMSVLQSQRVVTSTQSNPDDILTLSSSTESEGESGTSRKPTAGHTSATAVDSDDIQTISSGSDGDDFEDKKNLSGPTKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites