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Protein transport protein Sec31A

Summary

UniProt ID: O94979
Gene Symbol: SEC31A HSPC275 HSPC334 KIAA0905 SEC31L1
Gene ID: 22872
Organism: Homo sapiens (human)

External Links

GlyGen: O94979
PubChem: O94979
The Human Metabolome Database: HMDBP07990
The O-GlcNAc Database: O94979
O-GlcNAcAtlas: O94979
Re-Glyco: O94979

Annotation

Keyword: 3D-structure Alternative splicing Chromosomal rearrangement Cytoplasm Cytoplasmic vesicle ER-Golgi transport Endoplasmic reticulum Isopeptide bond Membrane Phosphoprotein Protein transport Proteomics identification Proto-oncogene Reference proteome Repeat Ubl conjugation WD repeat

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
endoplasmic reticulum to Golgi vesicle-mediated transport	NAS	PMID
endoplasmic reticulum to Golgi vesicle-mediated transport	IEA	GO_REF
endoplasmic reticulum organization	IBA	GO_REF
protein transport
response to calcium ion	IDA	PMID

GO Hierarchy

biological process

cellular process [inference]

intercellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

cellular localization [inference]

intracellular transport [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

endoplasmic reticulum organization

response to stimulus [inference]

response to chemical [inference]

response to metal ion [inference]

response to calcium ion

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

protein transport

vesicle-mediated transport [inference]

Golgi vesicle transport [inference]

endoplasmic reticulum to Golgi vesicle-mediated transport

vesicle cargo loading [inference]

COPII-coated vesicle cargo loading

intracellular transport [inference]

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

cellular localization [inference]

intracellular transport [inference]

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	Reference
cytoplasm	IDA	PMID
cytoplasm	IEA	GO_REF
endoplasmic reticulum	NAS	PMID
endoplasmic reticulum	IDA	PMID
endoplasmic reticulum membrane	TAS	Reactome Reactome Reactome Reactome Reactome

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat [inference]

vesicle coat

COPII vesicle coat

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

Displaying **all 2** entries
GO Term	Evidence Code	Reference
structural molecule activity	IBA	GO_REF
calcium-dependent protein binding	IPI	PMID PMID

GO Hierarchy

molecular function

structural molecule activity

binding [inference]

protein binding [inference]

calcium-dependent protein binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTGPQNGWNDPPALNRVPKKKKMPENFMPPVPITSPIMNPLGDPQSQMLQQQPSAPVPLSSQSSFPQPHLPGGQPFHGVQQPLGQTGMPPSFSKPNIEGAPGAPIGNTFQHVQSLPTKKITKKPIPDEHLILKTTFEDLIQRCLSSATDPQTKRKLDDASKRLEFLYDKLREQTLSPTITSGLHNIARSIETRNYSEGLTMHTHIVSTSNFSETSAFMPVLKVVLTQANKLGV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 29 in total

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Position	PubMed ID	GlyTouCan ID	Source
160	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	The O-GlcNAc Database
351	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	The O-GlcNAc Database
352	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	The O-GlcNAc Database
451	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	GlyGen The O-GlcNAc Database
658	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	GlyGen The O-GlcNAc Database
666	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	GlyGen The O-GlcNAc Database
674	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	GlyGen The O-GlcNAc Database
762	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	GlyGen The O-GlcNAc Database
774	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	GlyGen The O-GlcNAc Database
903	20305658 21740066 23301498 27655845 28510447 29161034 29351928 29913562 30397120 32119511 32870666 32885474 33214551 34019948 34142147 34229054 34725712 34931806 35008409 35138101 38253038 38665916 39302247 39531497 39534244 40596516 40914422	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Homo sapiens
COPII-mediated vesicle transport	Homo sapiens
MHC class II antigen presentation	Homo sapiens
Signaling by ALK fusions and activated point mutants	Homo sapiens
XBP1(S) activates chaperone genes	Homo sapiens

Human Protein Atlas

ENSG00000138674

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070539	Halperin-Birk syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements