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MIRAGE
Interleukin-18 receptor accessory protein
Summary
- UniProt ID
- O95256
- Gene Symbol
- IL18RAP IL1R7
- Gene ID
- 8807
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O95256
- PubChem
- O95256
- The Human Metabolome Database
- HMDBP12409
- Re-Glyco
- O95256
Annotation
- Keyword
- 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Hydrolase Immunoglobulin domain Inflammatory response NAD Proteomics identification Receptor Reference proteome Repeat Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| adaptive immune response |
|
|
| inflammatory response | ||
| immune response | ||
| cell population proliferation |
|
|
| interleukin-18-mediated signaling pathway |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| coreceptor activity | ||
| interleukin-18 receptor activity | ||
| interleukin-18 receptor activity | ||
| NAD+ nucleosidase activity, cyclic ADP-ribose generating |
GO Hierarchy
Sequence
MLCLGWIFLWLVAGERIKGFNISGCSTKKLLWTYSTRSEEEFVLFCDLPEPQKSHFCHRNRLSPKQVPEHLPFMGSNDLSDVQWYQQPSNGDPLEDIRKSYPHIIQDKCTLHFLTPGVNNSGSYICRPKMIKSPYDVACCVKMILEVKPQTNASCEYSASHKQDLLLGSTGSISCPSLSCQSDAQSPAVTWYKNGKLLSVERSNRIVVDEVYDYHQGTYVCDYTQSDTVSSWTVRAVVQVRTIVGDTKLKPDILDPVEDTLEVELGKPLTISCKARFGFERVFNPVIKWYIKDSDLEWEVSVPEAKSIKSTLKDEIIERNIILEKVTQRDLRRKFVCFVQNSIGNTTQSVQLKEKRGVVLLYILLGTIGTLVAVLAASALLYRHWIEIVLLYRTYQSKDQTLGDKKDFDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGPSIFELQAAVNLALDDQTLKLILIKFCYFQEPESLPHLVKKALRVLPTVTWRGLKSVPPNSRFWAKMRYHMPVKNSQGFTWNQLRITSRIFQWKGLSRTETTGRSSQPKEW
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 21 |
|
|
||
| 119 |
|
|
||
| 152 |
|
|
||
| 345 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-18 signaling | Homo sapiens |
