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MIRAGE
Rap guanine nucleotide exchange factor 3
Summary
- UniProt ID
- O95398
- Gene Symbol
-
- CGEF1
- EPAC
- EPAC1
- RAPGEF3
- Gene ID
- 10411
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O95398
- PubChem
- O95398
- The Human Metabolome Database
- HMDBP02762
- Re-Glyco
- O95398
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Guanine-nucleotide releasing factor
- Membrane
- Phosphoprotein
- Reference proteome
- cAMP-binding
- Gene Ontology (GO)
| GO Term |
|---|
| endomembrane system |
| membrane |
| lamellipodium |
| filopodium |
| extracellular exosome |
| plasma membrane |
| microvillus |
| GO Term |
|---|
| guanyl-nucleotide exchange factor activity |
| protein domain specific binding |
| cAMP binding |
Sequence
MKVGWPGESCWQVGLAVEDSPALGAPRVGALPDVVPEGTLLNMVLRRMHRPRSCSYQLLLEHQRPSCIQGLRWTPLTNSEESLDFSESLEQASTERVLRAGRQLHRHLLATCPNLIRDRKYHLRLYRQCCSGRELVDGILALGLGVHSRSQVVGICQVLLDEGALCHVKHDWAFQDRDAQFYRFPGPEPEPVRTHEMEEELAEAVALLSQRGPDALLTVALRKPPGQRTDEELDLIFEELLHIKAVAHLSNSVKRELAAVLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILREDNCHFLRVDKQDFNRIIKDVEAKTMRLEEHGKVVLVLERASQGAGPSRPPTPGRNRYTVMSGTPEKILELLLEAMGPDSSAHDPTETFLSDFLLTHRVFMPSAQLCAALLHHFHVEPAGGSEQERSTYVCNKRQQILRLVSQWVALYGSMLHTDPVATSFLQKLSDLVGRDTRLSNLLREQWPERRRCHRLENGCGNASPQMKARNLPVWLPNQDEPLPGSSCAIQVGDKVPYDICRPDHSVLTLQLPVTASVREVMAALAQEDGWTKGQVLVKVNSAGDAIGLQPDARGVATSLGLNERLFVVNPQEVHELIPHPDQLGPTVGSAEGLDLVSAKDLAGQLTDHDWSLFNSIHQVELIHYVLGPQHLRDVTTANLERFMRRFNELQYWVATELCLCPVPGPRAQLLRKFIKLAAHLKEQKNLNSFFAVMFGLSNSAISRLAHTWERLPHKVRKLYSALERLLDPSWNHRVYRLALAKLSPPVIPFMPLLLKDMTFIHEGNHTLVENLINFEKMRMMARAARMLHHCRSHNPVPLSPLRSRVSHLHEDSQVARISTCSEQSLSTRSPASTWAYVQQLKVIDNQRELSRLSRELEP
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | Homo sapiens |
| Integrin signaling | Homo sapiens |
| Rap1 signalling | Homo sapiens |
| Regulation of insulin secretion | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050742 | nicotine dependence |
