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Mast/stem cell growth factor receptor Kit

Summary

UniProt ID: O97799
Gene Symbol: KIT
Gene ID: 403811
Organism: Canis lupus familiaris (dog)

External Links

PubChem: O97799
Re-Glyco: O97799

Annotation

Keyword: ATP-binding Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Magnesium Metal-binding Phosphoprotein Proto-oncogene Receptor Reference proteome Repeat Signal Transmembrane helix Tyrosine-protein kinase Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of 83 in total

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GO Term	Evidence Code	Reference
ovarian follicle development	ISS	GO_REF
ovarian follicle development	IEA	GO_REF
hematopoietic progenitor cell differentiation	IBA	GO_REF
hematopoietic progenitor cell differentiation	IEA	GO_REF
myeloid progenitor cell differentiation

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte degranulation [inference]

mast cell degranulation

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

immature B cell differentiation

T cell differentiation

T cell activation [inference]

T cell differentiation

B cell activation [inference]

B cell differentiation

immature B cell differentiation

leukocyte migration [inference]

leukocyte chemotaxis [inference]

mast cell chemotaxis

myeloid leukocyte migration [inference]

mast cell migration [inference]

mast cell chemotaxis

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

immature B cell differentiation

T cell differentiation

T cell activation [inference]

T cell differentiation

B cell activation [inference]

B cell differentiation

immature B cell differentiation

cell adhesion [inference]

cell-cell adhesion [inference]

epithelial cell-cell adhesion [inference]

melanocyte adhesion

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

Kit signaling pathway

cytokine-mediated signaling pathway

intracellular signal transduction

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

carbohydrate derivative metabolic process [inference]

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process

cell death [inference]

programmed cell death [inference]

programmed cell death involved in cell development [inference]

ectopic germ cell programmed cell death

cell population proliferation [inference]

leukocyte proliferation [inference]

mast cell proliferation

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

spermatid development

actin filament-based process [inference]

actin cytoskeleton organization

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

ectopic germ cell programmed cell death

cell differentiation [inference]

hematopoietic progenitor cell differentiation

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

mast cell differentiation

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

immature B cell differentiation

T cell differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

mast cell differentiation

erythrocyte differentiation

stem cell differentiation

pigment cell differentiation [inference]

melanocyte differentiation

cell development [inference]

germ cell development [inference]

spermatid development

hemopoiesis [inference]

embryonic hemopoiesis

myeloid cell development [inference]

megakaryocyte development

cell motility [inference]

cell migration

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

melanocyte migration

hematopoietic stem cell migration

leukocyte migration [inference]

leukocyte chemotaxis [inference]

mast cell chemotaxis

myeloid leukocyte migration [inference]

mast cell migration [inference]

mast cell chemotaxis

cell chemotaxis

leukocyte chemotaxis [inference]

mast cell chemotaxis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

plasma membrane bounded cell projection organization [inference]

lamellipodium organization [inference]

lamellipodium assembly

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

spermatid development

reproductive structure development [inference]

gonad development [inference]

male gonad development

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

spermatid development

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

immature B cell differentiation

T cell differentiation

T cell activation [inference]

T cell differentiation

B cell activation [inference]

B cell differentiation

immature B cell differentiation

system process [inference]

nervous system process [inference]

detection of mechanical stimulus involved in sensory perception of sound

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

spermatid development

reproductive structure development [inference]

gonad development [inference]

male gonad development

anatomical structure development [inference]

ovarian follicle development

tube development [inference]

digestive tract development

cell development [inference]

germ cell development [inference]

spermatid development

hemopoiesis [inference]

embryonic hemopoiesis

myeloid cell development [inference]

megakaryocyte development

animal organ development [inference]

gonad development [inference]

male gonad development

embryonic organ development [inference]

embryonic hemopoiesis

reproductive structure development [inference]

gonad development [inference]

male gonad development

cellular developmental process [inference]

programmed cell death involved in cell development [inference]

ectopic germ cell programmed cell death

cell differentiation [inference]

hematopoietic progenitor cell differentiation

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

mast cell differentiation

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

immature B cell differentiation

T cell differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

mast cell differentiation

erythrocyte differentiation

stem cell differentiation

pigment cell differentiation [inference]

melanocyte differentiation

cell development [inference]

germ cell development [inference]

spermatid development

hemopoiesis [inference]

embryonic hemopoiesis

myeloid cell development [inference]

megakaryocyte development

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

leukocyte chemotaxis [inference]

mast cell chemotaxis

pigmentation

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to external stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to abiotic stimulus [inference]

response to radiation

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

response to mechanical stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of stimulus [inference]

detection of external stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of abiotic stimulus [inference]

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

detection of stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception [inference]

detection of mechanical stimulus involved in sensory perception of sound

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

secretion [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

export from cell [inference]

secretion by cell [inference]

exocytosis [inference]

regulated exocytosis [inference]

leukocyte degranulation [inference]

mast cell degranulation

establishment of localization in cell [inference]

leukocyte degranulation [inference]

mast cell degranulation

establishment of organelle localization [inference]

mast cell degranulation

organelle localization [inference]

establishment of organelle localization [inference]

mast cell degranulation

vacuolar localization [inference]

lysosome localization [inference]

mast cell degranulation

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of dendritic cell cytokine production

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of dendritic cell cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of dendritic cell cytokine production [inference]

positive regulation of dendritic cell cytokine production

regulation of mast cell cytokine production [inference]

positive regulation of mast cell cytokine production

regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of dendritic cell cytokine production

regulation of dendritic cell cytokine production [inference]

positive regulation of dendritic cell cytokine production

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of dendritic cell cytokine production

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mast cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of smooth muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

negative regulation of developmental process

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

cell surface receptor signaling pathway [inference]

immune response-regulating cell surface receptor signaling pathway [inference]

Fc receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

Kit signaling pathway

cytokine-mediated signaling pathway

intracellular signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of dendritic cell cytokine production [inference]

positive regulation of dendritic cell cytokine production

regulation of mast cell cytokine production [inference]

positive regulation of mast cell cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of dendritic cell cytokine production [inference]

positive regulation of dendritic cell cytokine production

regulation of mast cell cytokine production [inference]

positive regulation of mast cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of dendritic cell cytokine production [inference]

positive regulation of dendritic cell cytokine production

regulation of mast cell cytokine production [inference]

positive regulation of mast cell cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of dendritic cell cytokine production [inference]

positive regulation of dendritic cell cytokine production

regulation of mast cell cytokine production [inference]

positive regulation of mast cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mast cell proliferation

regulation of leukocyte proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mast cell proliferation

regulation of mast cell proliferation [inference]

positive regulation of mast cell proliferation

regulation of programmed cell death [inference]

negative regulation of programmed cell death

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of muscle cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of smooth muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

regulation of vascular associated smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mast cell proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell differentiation [inference]

positive regulation of muscle cell differentiation [inference]

positive regulation of smooth muscle cell differentiation [inference]

positive regulation of vascular associated smooth muscle cell differentiation

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of programmed cell death

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of dendritic cell cytokine production [inference]

positive regulation of dendritic cell cytokine production

regulation of mast cell cytokine production [inference]

positive regulation of mast cell cytokine production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of dendritic cell cytokine production

positive regulation of myeloid leukocyte cytokine production involved in immune response [inference]

positive regulation of mast cell cytokine production

regulation of reproductive process [inference]

negative regulation of reproductive process

regulation of biological quality [inference]

regulation of cell shape

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
fibrillar center
obsolete extracellular space
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF GO_REF GO_REF GO_REF
cell-cell junction	IEA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

cellular anatomical structure [inference]

fibrillar center

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
protease binding	IEA	GO_REF
transmembrane receptor protein tyrosine kinase activity	ISS	GO_REF
transmembrane receptor protein tyrosine kinase activity	IBA	GO_REF
transmembrane receptor protein tyrosine kinase activity	IEA	GO_REF GO_REF GO_REF GO_REF GO_REF
stem cell factor receptor activity	IEA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

stem cell factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

stem cell factor receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

stem cell factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

stem cell factor receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

stem cell factor receptor activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

stem cell factor receptor activity

binding [inference]

protein binding [inference]

growth factor binding

enzyme binding [inference]

protease binding

protein domain specific binding [inference]

SH2 domain binding

cytokine binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

stem cell factor receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MRGARGAWDFLCVLLLLLLLGVQTGSSQPSVSPGEPSLPSIHPAKSELIVSVGDELRLSCTDPGFVKWTFETLGQLNENTHNEWITEKAEAGHTGNYTCTNRDGLSRSIYVFVRDPAKLFLVDLPLYGKEGNDTLVRCPLTDPEVTNYSLRGCEGKPLPKDLTFVADPKAGITIRNVKREYHRLCLHCSADQKGRTVLSKKFTLKVRAAIRAVPVVSVSKTSSLLKEGEAFSVMCFIKDVSSFVDSMWIKENSQQTNAQTQSNSWHHGDFNFERQEKLIISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMMSTTIFVNDGENVDLIVEYEAYPKPEHQQWIYMNRTFTDKWEDYPKSDNESNIRYVSELHLTRLKGNEGGTYTFQVSNSDVNSSVTFNVYVNTKPEILTHESLTNGMLQCVVAGFPEPAVDWYFCPGAEQRCSVPIGPMDVQMQNSSLSPSGKLVVQSSIDYSAFKHNGTVECRAYNNVGRSSAFFNFAFKGNSKEQIHPHTLFTPLLIGFVIAAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHGEVALYKNLLHSKESSCSDSTNEYMDMKPGVSYVVPTKADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISDSTNHIYSNLANCSPNPERPVVDHSVRINSVGSSASSTQPLLVHEDV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 11 in total

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Position	Description	Source
96	N-linked (GlcNAc...) asparagine	UniProt
132	N-linked (GlcNAc...) asparagine	UniProt
147	N-linked (GlcNAc...) asparagine	UniProt
286	N-linked (GlcNAc...) asparagine	UniProt
296	N-linked (GlcNAc...) asparagine	UniProt
303	N-linked (GlcNAc...) asparagine	UniProt
355	N-linked (GlcNAc...) asparagine	UniProt
370	N-linked (GlcNAc...) asparagine	UniProt
403	N-linked (GlcNAc...) asparagine	UniProt
466	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
PI3K/AKT Signaling	Canis familiaris
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Canis familiaris
RAF/MAP kinase cascade	Canis familiaris
Regulation of KIT signaling	Canis familiaris
Signaling by SCF-KIT	Canis familiaris
Transcriptional and post-translational regulation of MITF-M expression and activity	Canis familiaris

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements