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Tyrosine-protein kinase ABL1
Summary
- UniProt ID
- P00520
- Gene Symbol
-
- Abl
- Abl1
- Gene ID
- 11350
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Apoptosis
- Autophagy
- Cell adhesion
- Chromosomal rearrangement
- Cytoskeleton
- DNA repair
- DNA-binding
- Endocytosis
- Magnesium
- Manganese
- Metal-binding
- Mitochondrion
- Myristate
- Nucleus
- Phosphoprotein
- Proto-oncogene
- Reference proteome
- SH2 domain
- SH3 domain
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| nucleolus |
| cytoplasm |
| mitochondrion |
| actin cytoskeleton |
| dendrite |
| protein-containing complex |
| neuron projection |
| neuronal cell body |
| cytosol |
| GO Term |
|---|
| actin cytoskeleton organization |
| response to endoplasmic reticulum stress |
| positive regulation of neuron apoptotic process |
| transitional one stage B cell differentiation |
Sequence
MLEICLKLVGCKSKKGLSSSSSCYLEEALQRPVASDFEPQGLSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKPTIYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKRGTRGGAGSMLQAPELPTKTRTCRRAAEQKDAPDTPELLHTKGLGESDALDSEPAVSPLLPRKERGPPDGSLNEDERLLPRDRKTNLFSALIKKKKKMAPTPPKRSSSFREMDGQPDRRGASEDDSRELCNGPPALTSDAAEPTKSPKASNGAGVPNGAFREPGNSGFRSPHMWKKSSTLTGSRLAAAEEESGMSSSKRFLRSCSASCMPHGARDTEWRSVTLPRDLPSAGKQFDSSTFGGHKSEKPALPRKRTSESRSEQVAKSTAMPPPRLVKKNEEAAEEGFKDTESSPGSSPPSLTPKLLRRQVTASPSSGLSHKEEATKGSASGMGTPATAEPAPPSNKVGLSKASSEEMRVRRHKHSSESPGRDKGRLAKLKPAPPPPPACTGKAGKPAQSPSQEAGEAGGPTKTKCTSLAMDAVNTDPTKAGPPGEGLRKPVPPSVPKPQSTAKPPGTPTSPVSTPSTAPAPSPLAGDQQPSSAAFIPLISTRVSLRKTRQPPERIASGTITKGVVLDSTEALCLAISRNSEQMASHSAVLEAGKNLYTFCVSYVDSIQQMRNKFAFREAINKLESNLRELQICPATASSGPAATQDFSKLLSSVKEISDIVRR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 187 |
|
|||
| 613 |
|
|
||
| 974 |
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cyclin D associated events in G1 | Mus musculus |
| HDR through Single Strand Annealing (SSA) | Mus musculus |
| MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis | Mus musculus |
| Myogenesis | Mus musculus |
| RHO GTPases Activate WASPs and WAVEs | Mus musculus |
| RUNX1 regulates transcription of genes involved in differentiation of HSCs | Mus musculus |
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | Mus musculus |
| Regulation of actin dynamics for phagocytic cup formation | Mus musculus |
| Role of ABL in ROBO-SLIT signaling | Mus musculus |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | Mus musculus |
