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MIRAGE
Immunoglobulin heavy constant gamma 2B
Summary
- UniProt ID
- P01867
- Gene Symbol
- Ighg2b Igh-3
- Gene ID
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003255
- GlyConnect
- GlyGen
- P01867
- Re-Glyco
- P01867
Annotation
- Keyword
- 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein Immunoglobulin domain Reference proteome Repeat Secreted Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| positive regulation of type IIa hypersensitivity | ||
| positive regulation of type IIa hypersensitivity | ||
| positive regulation of type I hypersensitivity | ||
| positive regulation of type I hypersensitivity | ||
| humoral immune response mediated by circulating immunoglobulin |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| obsolete extracellular space |
|
|
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| antigen binding | ||
| antigen binding | ||
| antigen binding | ||
| immunoglobulin receptor binding | ||
| Fc-gamma receptor I complex binding |
Sequence
KTTPPSVYPLAPGCGDTTGSSVTLGCLVKGYFPESVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSQTVTCSVAHPASSTTVDKKLEPSGPISTINPCPPCKECHKCPAPNLEGGPSVFIFPPNIKDVLMISLTPKVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTIRVVSTLPIQHQDWMSGKEFKCKVNNKDLPSPIERTISKIKGLVRAPQVYILPPPAEQLSRKDVSLTCLVVGFNPGDISVEWTSNGHTEENYKDTAPVLDSDGSYFIYSKLNMKTSKWEKTDSFSCNVRHEGLKNYYLKKTISRSPGLDLDDICAEAKDGELDGLWTTITIFISLFLLSVCYSASVTLFKVKWIFSSVVELKQKISPDYRNMIGQGA
Glycosylation Sites
G15488CF
G39397SW
G07075ND
G64161CC
G78224CS
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Classical antibody-mediated complement activation | Mus musculus |
| FCGR activation | Mus musculus |
| Regulation of Complement cascade | Mus musculus |
| Regulation of actin dynamics for phagocytic cup formation | Mus musculus |
| Role of phospholipids in phagocytosis | Mus musculus |
