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Large T antigen

Summary

UniProt ID

P03070

Gene Symbol

Organism

Betapolyomavirus macacae

External Links

GlyConnect

Large t antigen

PubChem

P03070

Re-Glyco

P03070

Annotation

Keyword

3D-structure
Acetylation
Activator
Alternative initiation
Alternative splicing
DNA replication
DNA-binding
Direct protein sequencing
Early protein
G1/S host cell cycle checkpoint dysregulation by virus
Glycoprotein
Helicase
Host nucleus
Inhibition of host JAK1 by virus
Isomerase
Magnesium
Modulation of host E3 ubiquitin ligases by virus
Oncogene
Phosphoprotein
Reference proteome
Transcription regulation
Zinc-finger

Gene Ontology (GO)

Displaying 1 entry
GO Term
host cell nucleus

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
modulation by symbiont of host protein ubiquitination
virus-mediated perturbation of host defense response
suppression by virus of host type I interferon-mediated signaling pathway
suppression of host innate immune response
DNA unwinding involved in DNA replication
bidirectional double-stranded viral DNA replication
disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity
perturbation by virus of host G1/S transition checkpoint
viral DNA genome replication

Displaying **all 9** entries
GO Term
isomerase activity
metal ion binding
double-stranded DNA binding
helicase activity
ATP binding
ATP hydrolysis activity
identical protein binding
single-stranded DNA binding
DNA replication origin binding

Annotation information from UniProt.

Sequence

MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHETGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites