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Acetylcholinesterase

Summary

UniProt ID: P04058
Gene Symbol: ache
Gene ID
Organism: Tetronarce californica (Pacific electric ray)

External Links

PubChem: P04058
Re-Glyco: P04058

Annotation

Keyword: 3D-structure Alternative splicing Cell membrane Direct protein sequencing Disulfide bond GPI-anchor Neurotransmitter degradation Serine esterase Signal Synapse

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	Reference
acetylcholine catabolic process in synaptic cleft	IEA	GO_REF
choline metabolic process	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

acetylcholine metabolic process [inference]

acetylcholine catabolic process [inference]

acetylcholine catabolic process in synaptic cleft

catabolic process [inference]

acetylcholine catabolic process [inference]

acetylcholine catabolic process in synaptic cleft

choline metabolic process

Displaying **all 5** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
plasma membrane	IEA	GO_REF GO_REF
synaptic cleft	IEA	GO_REF
synapse	IEA	GO_REF
side of membrane

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

Displaying 1 entry
GO Term	Evidence Code	Reference
acetylcholinesterase activity	IEA	GO_REF GO_REF GO_REF GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

carboxylic ester hydrolase activity [inference]

cholinesterase activity [inference]

acetylcholinesterase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MNLLVTSSLGVLLHLVVLCQADDHSELLVNTKSGKVMGTRVPVLSSHISAFLGIPFAEPPVGNMRFRRPEPKKPWSGVWNASTYPNNCQQYVDEQFPGFSGSEMWNPNREMSEDCLYLNIWVPSPRPKSTTVMVWIYGGGFYSGSSTLDVYNGKYLAYTEEVVLVSLSYRVGAFGFLALHGSQEAPGNVGLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGSPNCPWASVSVAEGRRRAVELGRNLNCNLNSDEELIHCLREKKPQELIDVEWNVLPFDSIFRFSFVPVIDGEFFPTSLESMLNSGNFKKTQILLGVNKDEGSFFLLYGAPGFSKDSESKISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMDDNNGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFGNGTYLYFFNHRASNLVWPEWMGVIHGYEIEFVFGLPLVKELNYTAEEEALSRRIMHYWATFAKTGNPNEPHSQESKWPLFTTKEQKFIDLNTEPMKVHQRLRVQMCVFWNQFLPKLLNATACDGELSSSGTSSSKGIIFYVLFSILYLIF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	Source
80	N-linked (GlcNAc...) asparagine	10368299 16763558	UniProt
437	N-linked (GlcNAc...) asparagine	10368299 16763558 1678899	UniProt
478	N-linked (GlcNAc...) asparagine	10368299	UniProt
554	N-linked (GlcNAc...) asparagine	10368299	UniProt