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Proenkephalin-A
Summary
- UniProt ID
- P04094
- Gene Symbol
- Penk Penk-rs Penk1
- Gene ID
- 29237
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- Cleavage on pair of basic residues Cytoplasmic vesicle Direct protein sequencing Disulfide bond Endorphin Neuropeptide Opioid peptide Phosphoprotein Reference proteome Secreted Signal
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| osteoblast differentiation | ||
| behavioral fear response | ||
| response to hypoxia | ||
| startle response | ||
| aggressive behavior |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| plasma membrane |
|
|
| axon | ||
| dendrite |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| opioid peptide activity | ||
| opioid peptide activity | ||
| opioid receptor binding | ||
| receptor ligand activity | ||
| receptor ligand activity |
GO Hierarchy
Sequence
MAQFLRLCIWLLALGSCLLATVQADCSQDCAKCSYRLVRPGDINFLACTLECEGQLPSFKIWETCKDLLQVSKPEFPWDNIDMYKDSSKQDESHLLAKKYGGFMKRYGGFMKKMDELYPVEPEEEANGGEILAKRYGGFMKKDADEGDTLANSSDLLKELLGTGDNRAKDSHQQESTNNDEDSTSKRYGGFMRGLKRSPQLEDEAKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAESLPSDEEGESYSKEVPEMEKRYGGFMRF
Glycosylation Sites
G19379ID
G88725PI
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| G alpha (i) signalling events | Rattus norvegicus |
| Peptide ligand-binding receptors | Rattus norvegicus |
| Post-translational protein phosphorylation | Rattus norvegicus |
| Regulation of IGF Activity by IGFBP | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9976 | heroin dependence |
