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Myelin basic protein

Summary

UniProt ID

P04370

Gene Symbol

Mbp
Shi

Gene ID

17196

Organism

Mus musculus (house mouse)

External Links

GlyGen: P04370
PubChem: P04370
O-GlcNAcAtlas: P04370
Re-Glyco: P04370

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Autoimmune encephalomyelitis
Cell membrane
Citrullination
Cytoplasm
Direct protein sequencing
Methylation
Nucleus
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
compact myelin
internode region of axon
nucleus
cytoplasm
plasma membrane
protein-containing complex
cell projection
neuronal cell body
myelin sheath
cell periphery

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 10** entries
GO Term
negative regulation of heterotypic cell-cell adhesion
maintenance of blood-brain barrier
positive regulation of metalloendopeptidase activity
MAPK cascade
positive regulation of interleukin-6 production
sensory perception of sound
response to toxic substance
myelination
membrane organization
positive regulation of chemokine (C-X-C motif) ligand 2 production

Displaying **all 3** entries
GO Term
protease binding
calmodulin binding
structural constituent of myelin sheath

Annotation information from UniProt.

Sequence

MGNHSGKRELSAEKASKDGEIHRGEAGKKRSVGKLSQTASEDSDVFGEADAIQNNGTSAEDTAVTDSKHTADPKNNWQGAHPADPGNRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDPTAASGGLDVMASQKRPSQRSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFSGDRGAPKRGSGKDSHTRTTHYGSLPQKSQHGRTQDENPVVHFFKNIVTPRTPPPSQGKGGRDSRSGSPMARR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites