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MIRAGE
Interleukin-5
Summary
- UniProt ID
- P05113
- Gene Symbol
- IL5
- Gene ID
- 3567
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P05113
- PubChem
- P05113
- The Human Metabolome Database
- HMDBP02456
- Re-Glyco
- P05113
Annotation
- Keyword
- 3D-structure Alternative splicing Cytokine Direct protein sequencing Disulfide bond Glycoprotein Growth factor Reference proteome Secreted Signal
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| positive regulation of immunoglobulin production | ||
| inflammatory response | ||
| immune response | ||
| positive regulation of B cell proliferation | ||
| interleukin-5-mediated signaling pathway |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of cellular component biogenesis [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| obsolete extracellular space |
|
|
| GO Term | Evidence Code | Reference |
|---|---|---|
| cytokine activity | ||
| cytokine activity | ||
| cytokine activity | ||
| interleukin-5 receptor binding | ||
| interleukin-5 receptor binding |
GO Hierarchy
- Site Annotations
| Position | Description |
|---|---|
| 90 | Not glycosylated |
Sequence
MRMLLHLSLLALGAAYVYAIPTEIPTSALVKETLALLSTHRTLLIANETLRIPVPVHKNHQLCTEEIFQGIGTLESQTVQGGTVERLFKNLSLIKKYIDGQKKKCGEERRRVNQFLDYLQEFLGVMNTEWIIES
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Differentiation of naive CD4+ T cells to T helper 2 cells (Th2 cells) | Homo sapiens |
| Interleukin receptor SHC signaling | Homo sapiens |
| Interleukin-3, Interleukin-5 and GM-CSF signaling | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10534 | stomach cancer | |
| DOID:2841 | asthma |
