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MIRAGE
Proto-oncogene tyrosine-protein kinase Src
Summary
- UniProt ID
- P05480
- Gene Symbol
- Src
- Gene ID
- 20779
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
- 3D-structure ATP-binding Alternative splicing Cell adhesion Cell cycle Cell junction Cell membrane Cytoskeleton Immunity Mitochondrion inner membrane Myristate Nucleus Phosphoprotein Proto-oncogene Reference proteome SH2 domain SH3 domain Tyrosine-protein kinase Ubl conjugation
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| primary ovarian follicle growth | ||
| positive regulation of cytokine production | ||
| cell adhesion |
GO Hierarchy
- positive regulation of cell adhesion
- positive regulation of cell adhesion
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
positive regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of signaling [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation
positive regulation of metabolic process [inference]
positive regulation of cell communication [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
positive regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of cell adhesion [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
positive regulation of cell population proliferation
positive regulation of metabolic process [inference]
positive regulation of cell communication [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| protein kinase activity | ||
| protein kinase activity | ||
| protein kinase activity | ||
| protein kinase activity | ||
| protein tyrosine kinase activity |
GO Hierarchy
Sequence
MGSNKSKPKDASQRRRSLEPSENVHGAGGAFPASQTPSKPASADGHRGPSAAFVPPAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
Glycosylation Sites
G43769HG
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ADP signalling through P2Y purinoceptor 1 | Mus musculus |
| Activated NTRK3 signals through PI3K | Mus musculus |
| CD28 co-stimulation | Mus musculus |
| CLEC7A (Dectin-1) signaling | Mus musculus |
| Co-inhibition by CTLA4 | Mus musculus |
| Cyclin D associated events in G1 | Mus musculus |
| DCC mediated attractive signaling | Mus musculus |
| Degradation of CDH1 | Mus musculus |
| Downregulation of ERBB4 signaling | Mus musculus |
| Downstream signal transduction | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1928 | Williams-Beuren syndrome |
