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MIRAGE
5,6-dihydroxyindole-2-carboxylic acid oxidase
Summary
- UniProt ID
- P07147
- Gene Symbol
-
- Tyrp-1
- Tyrp1
- Gene ID
- 22178
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Albinism
- Copper
- Disease variant
- Disulfide bond
- Glycoprotein
- Melanin biosynthesis
- Metal-binding
- Monooxygenase
- Reference proteome
- Signal
- Transmembrane helix
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| melanosome |
| endosome membrane |
| clathrin-coated endocytic vesicle membrane |
| melanosome membrane |
| GO Term |
|---|
| identical protein binding |
| protein homodimerization activity |
| tyrosinase activity |
| metal ion binding |
Sequence
MKSYNVLPLAYISLFLMLFYQVWAQFPRECANIEALRRGVCCPDLLPSSGPGTDPCGSSSGRGRCVAVIADSRPHSRHYPHDGKDDREAWPLRFFNRTCQCNDNFSGHNCGTCRPGWRGAACNQKILTVRRNLLDLSPEEKSHFVRALDMAKRTTHPQFVIATRRLEDILGPDGNTPQFENISVYNYFVWTHYYSVKKTFLGTGQESFGDVDFSHEGPAFLTWHRYHLLQLERDMQEMLQEPSFSLPYWNFATGKNVCDVCTDDLMGSRSNFDSTLISPNSVFSQWRVVCESLEEYDTLGTLCNSTEGGPIRRNPAGNVGRPAVQRLPEPQDVTQCLEVRVFDTPPFYSNSTDSFRNTVEGYSAPTGKYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNADISTFPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYAYEVQWPGQEFTVSEIITIAVVAALLLVAAIFGVASCLIRSRSTKNEANQPLLTDHYQRYAEDYEELPNPNHSMV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 96 | N-linked (GlcNAc...) asparagine |
|
||
| 104 | N-linked (GlcNAc...) asparagine |
|
||
| 181 | N-linked (GlcNAc...) asparagine |
|
||
| 304 | N-linked (GlcNAc...) asparagine |
|
||
| 350 | N-linked (GlcNAc...) asparagine |
|
||
| 385 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Melanin biosynthesis | Mus musculus |
