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Integrin beta-1

Summary

UniProt ID: P09055
Gene Symbol: Itgb1
Gene ID: 16412
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003318

GlyConnect

Integrin beta-1

GlyGen

P09055

PubChem

P09055

The O-GlcNAc Database

P09055

RaftProt

P09055

Re-Glyco

P09055

Annotation

Keyword: 3D-structure Acetylation Alternative splicing Calcium Cell adhesion Cell junction Cell membrane Cell projection Disulfide bond EGF-like domain Endosome Glycoprotein Integrin Isopeptide bond Magnesium Metal-binding Myogenesis Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 5** of **114** in total

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GO Term	Evidence Code	Reference
G1/S transition of mitotic cell cycle	IMP	PMID
establishment of mitotic spindle orientation	ISO	GO_REF
establishment of mitotic spindle orientation	IEA	GO_REF
angiogenesis	ISO	GO_REF
angiogenesis	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

microtubule cytoskeleton organization involved in mitosis [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

cell adhesion

cell-substrate adhesion

cell-matrix adhesion

calcium-independent cell-matrix adhesion

cell adhesion mediated by integrin

cell-cell adhesion mediated by integrin

cell-cell adhesion

leukocyte cell-cell adhesion

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

phagocytosis

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

spindle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

mitotic cell cycle process [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

microtubule cytoskeleton organization involved in mitosis [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

sarcomere organization

cellular developmental process [inference]

cell fate specification

cell differentiation [inference]

cardiocyte differentiation [inference]

cardiac muscle cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

cardiac muscle cell differentiation

cell motility [inference]

cell migration

germ cell migration

endothelial cell migration [inference]

blood vessel endothelial cell migration [inference]

cell migration involved in sprouting angiogenesis

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport within lipid bilayer

cellular response to stimulus [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

microtubule cytoskeleton organization involved in mitosis [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

sarcomere organization

postsynaptic specialization organization [inference]

postsynaptic density organization [inference]

maintenance of postsynaptic specialization structure

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

cell projection organization

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

plasma membrane bounded cell projection organization [inference]

neuron projection development

lamellipodium organization [inference]

lamellipodium assembly

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

cell junction maintenance [inference]

maintenance of synapse structure [inference]

maintenance of postsynaptic specialization structure

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

tight junction organization [inference]

tight junction assembly [inference]

bicellular tight junction assembly

synapse organization [inference]

maintenance of synapse structure [inference]

maintenance of postsynaptic specialization structure

extracellular structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

cellular component maintenance [inference]

cell junction maintenance [inference]

maintenance of synapse structure [inference]

maintenance of postsynaptic specialization structure

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

basement membrane organization

membrane organization [inference]

protein transport within lipid bilayer

cell-cell fusion [inference]

syncytium formation by cell-cell fusion [inference]

myoblast fusion

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

visual behavior [inference]

visual learning

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

formation of radial glial scaffolds

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

tissue development [inference]

muscle tissue development [inference]

striated muscle tissue development [inference]

cardiac muscle tissue development

animal organ development [inference]

muscle organ development

muscle structure development [inference]

muscle organ development

cellular developmental process [inference]

cell fate specification

cell differentiation [inference]

cardiocyte differentiation [inference]

cardiac muscle cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

cardiac muscle cell differentiation

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension

developmental growth involved in morphogenesis [inference]

neuron projection extension [inference]

axon extension

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

neuroinflammatory response [inference]

reactive gliosis

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

response to endogenous stimulus [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

response to activity [inference]

response to muscle activity

response to chemical [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

cellular response to stimulus [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport within lipid bilayer

establishment of localization [inference]

transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport within lipid bilayer

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

phagocytosis

intracellular transport [inference]

intracellular protein transport [inference]

protein transport within lipid bilayer

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

phagocytosis

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport within lipid bilayer

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport within lipid bilayer

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

establishment of organelle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

organelle localization [inference]

spindle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

establishment of organelle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport within lipid bilayer

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of fibroblast growth factor receptor signaling pathway [inference]

positive regulation of fibroblast growth factor receptor signaling pathway

regulation of vascular endothelial growth factor signaling pathway [inference]

positive regulation of vascular endothelial growth factor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rho protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of spontaneous synaptic transmission

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of transport [inference]

regulation of organic acid transport [inference]

regulation of L-glutamate import across plasma membrane [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of organic acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of L-glutamate import across plasma membrane [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of endocytosis

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter uptake [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amine transport [inference]

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amino acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of L-glutamate import across plasma membrane [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of cellular localization [inference]

regulation of postsynaptic neurotransmitter receptor diffusion trapping

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of receptor localization to synapse [inference]

regulation of postsynaptic neurotransmitter receptor diffusion trapping

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of fibroblast migration [inference]

positive regulation of fibroblast migration

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of endocytosis

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to wounding [inference]

positive regulation of wound healing

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of endocytosis

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of anoikis

negative regulation of cell differentiation

negative regulation of neuron differentiation

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of developmental process [inference]

negative regulation of cell differentiation

negative regulation of neuron differentiation

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of fibroblast growth factor receptor signaling pathway [inference]

positive regulation of fibroblast growth factor receptor signaling pathway

regulation of vascular endothelial growth factor signaling pathway [inference]

positive regulation of vascular endothelial growth factor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rho protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to wounding [inference]

positive regulation of wound healing

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of response to stress [inference]

regulation of response to wounding [inference]

regulation of wound healing [inference]

positive regulation of wound healing

positive regulation of response to wounding [inference]

positive regulation of wound healing

regulation of cellular response to growth factor stimulus [inference]

regulation of fibroblast growth factor receptor signaling pathway [inference]

positive regulation of fibroblast growth factor receptor signaling pathway

regulation of cellular response to vascular endothelial growth factor stimulus [inference]

regulation of vascular endothelial growth factor signaling pathway [inference]

positive regulation of vascular endothelial growth factor signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

regulation of cell differentiation [inference]

negative regulation of cell differentiation

negative regulation of neuron differentiation

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

negative regulation of developmental process [inference]

negative regulation of cell differentiation

negative regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of fibroblast growth factor receptor signaling pathway [inference]

positive regulation of fibroblast growth factor receptor signaling pathway

regulation of vascular endothelial growth factor signaling pathway [inference]

positive regulation of vascular endothelial growth factor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Rho protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of spontaneous synaptic transmission

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of collagen catabolic process

regulation of collagen metabolic process [inference]

regulation of collagen catabolic process

regulation of cell adhesion [inference]

regulation of cell-substrate adhesion [inference]

positive regulation of cell-substrate adhesion

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion

regulation of transmembrane transport [inference]

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of L-glutamate import across plasma membrane [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of cell population proliferation [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

negative regulation of apoptotic process

negative regulation of anoikis

regulation of anoikis [inference]

negative regulation of anoikis

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of anoikis

regulation of cell differentiation [inference]

negative regulation of cell differentiation

negative regulation of neuron differentiation

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of endocytosis

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of anoikis

negative regulation of cell differentiation

negative regulation of neuron differentiation

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of cell projection organization [inference]

negative regulation of cell projection organization

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development

regulation of synapse organization [inference]

regulation of synapse pruning

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development

positive regulation of endocytosis

regulation of cell cycle

regulation of cellular localization [inference]

regulation of postsynaptic neurotransmitter receptor diffusion trapping

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of fibroblast migration [inference]

positive regulation of fibroblast migration

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

regulation of postsynaptic neurotransmitter receptor diffusion trapping

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GO Term	Evidence Code	Reference
acrosomal vesicle	ISO	GO_REF
basement membrane	ISO	GO_REF
cytoplasm	ISO	GO_REF
cytoplasm	IEA	GO_REF
plasma membrane	ISS	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

plasma membrane signaling receptor complex [inference]

integrin complex

protein complex involved in cell adhesion [inference]

integrin complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

cellular anatomical structure [inference]

membrane

plasma membrane

sarcolemma

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

synaptic membrane

postsynaptic membrane

membrane microdomain [inference]

membrane raft

cell junction [inference]

synapse

neuromuscular junction

excitatory synapse [inference]

asymmetric, glutamatergic, excitatory synapse [inference]

cerebellar climbing fiber to Purkinje cell synapse

glutamatergic synapse

asymmetric, glutamatergic, excitatory synapse [inference]

cerebellar climbing fiber to Purkinje cell synapse

neuron to neuron synapse [inference]

asymmetric synapse [inference]

asymmetric, glutamatergic, excitatory synapse [inference]

cerebellar climbing fiber to Purkinje cell synapse

anchoring junction [inference]

cell-cell junction

adherens junction

cell-cell contact zone [inference]

intercalated disc

cell-substrate junction [inference]

external encapsulating structure [inference]

extracellular matrix [inference]

basement membrane

leading edge membrane [inference]

ruffle membrane

myelin sheath abaxonal region

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

neuron projection [inference]

neuron spine [inference]

dendritic spine

glial cell projection

actin-based cell projection [inference]

filopodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

pigment granule [inference]

melanosome

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

pigment granule [inference]

melanosome

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

pigment granule [inference]

melanosome

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

perinuclear region of cytoplasm

side of membrane [inference]

external side of plasma membrane

postsynapse [inference]

dendritic spine

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GO Term	Evidence Code	Reference
magnesium ion binding	ISO	GO_REF
magnesium ion binding	IEA	GO_REF
fibronectin binding	ISO	GO_REF GO_REF
fibronectin binding	IBA	GO_REF
fibronectin binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

fibronectin binding

signaling receptor binding

integrin binding

integrin binding involved in cell-matrix adhesion

cytoskeletal protein binding [inference]

actin binding

actinin binding [inference]

alpha-actinin binding

enzyme binding [inference]

protease binding

kinase binding

protein kinase binding

protein tyrosine kinase binding

protein domain specific binding

cytokine binding [inference]

chemokine binding [inference]

C-X3-C chemokine binding

laminin binding

protein dimerization activity [inference]

protein heterodimerization activity

cell adhesion molecule binding

integrin binding

integrin binding involved in cell-matrix adhesion

cell adhesion mediator activity [inference]

cell-matrix adhesion mediator activity [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

protein-containing complex binding

integrin binding

integrin binding involved in cell-matrix adhesion

collagen binding

collagen binding involved in cell-matrix adhesion

extracellular matrix binding [inference]

laminin binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MNLQLVSWIGLISLICSVFGQTDKNRCLKANAKSCGECIQAGPNCGWCTNTTFLQEGMPTSARCDDLEALKKKGCQPSDIENPRGSQTIKKNKNVTNRSKGMAEKLRPEDITQIQPQQLLLKLRSGEPQKFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTDRGEFFNELVGQQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENNVYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSGNSSNVIQLIIDAYNSLSSEVILENSKLPDGVTINYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITANKCPNKESETIKIKPLGFTEEVEVVLQFICKCNCQSHGIPASPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCRCRVCECYPNYTGSACDCSLDTGPCLASNGQICNGRGICECGACKCTDPKFQGPTCETCQTCLGVCAEHKECVQCRAFNKGEKKDTCAQECSHFNLTKVESREKLPQPVQVDPVTHCKEKDIDDCWFYFTYSVNGNNEAIVHVVETPDCPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

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Position	Description	PubMed ID	GlyTouCan ID	Source
50	N-linked (GlcNAc...) asparagine	30899004	G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
94	N-linked (GlcNAc...) asparagine		G41071NU	UniProt GlyGen
97	N-linked (GlcNAc...) asparagine		G41247ZX	UniProt GlyGen
212	N-linked (GlcNAc...) asparagine		G40024DP G54678CA G57471MV G44437FL G00490MQ G25079LO G02281EI G13749ZZ G31040BO	GlycoProtDB UniProt GlyGen
269	N-linked (GlcNAc...) asparagine			UniProt GlyGen
363	N-linked (GlcNAc...) asparagine	19656770		GlycoProtDB UniProt GlyGen
406	N-linked (GlcNAc...) asparagine		G02815KT	GlycoProtDB UniProt GlyGen
417	N-linked (GlcNAc...) asparagine		G46503DX	GlycoProtDB UniProt GlyGen
481	N-linked (GlcNAc...) asparagine	30899004	G70101JE G80920RR	GlycoProtDB UniProt GlyGen GlyConnect
520	N-linked (GlcNAc...) asparagine		G27947YN G40024DP G57471MV G44437FL G02281EI G13749ZZ	GlycoProtDB UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

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Pathway Name	Organism
Basigin interactions	Mus musculus
Cell surface interactions at the vascular wall	Mus musculus
ECM proteoglycans	Mus musculus
Elastic fibre formation	Mus musculus
Fibronectin matrix formation	Mus musculus
GPER1 signaling	Mus musculus
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Mus musculus
Integrin cell surface interactions	Mus musculus
Laminin interactions	Mus musculus
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	Mus musculus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10487	Hirschsprung's disease	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements