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EEF1AKMT4-ECE2 readthrough transcript protein [Includes: Methyltransferase-like region; Endothelin-converting enzyme 2 region]

Summary

UniProt ID: P0DPD8
Gene Symbol: ECE2 EEF1AKMT4-ECE2 KIAA0604 UNQ403/PRO740
Gene ID: 110599583
Organism: Homo sapiens (human)

External Links

GlyGen: P0DPD8
PubChem: P0DPD8
The Human Metabolome Database: HMDBP12655
The O-GlcNAc Database: P0DPD8
Re-Glyco: P0DPD8

Annotation

Keyword: Alternative splicing Cytoplasmic vesicle Disulfide bond Glycoprotein Golgi apparatus Metal-binding Metalloprotease Methyltransferase Multifunctional enzyme Phosphoprotein Reference proteome Transmembrane helix Zinc

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
brain development	ISS	GO_REF
heart development	ISS	GO_REF
cardioblast differentiation	ISS	GO_REF
protein processing	IBA	GO_REF
peptide hormone processing	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

methylation

hormone metabolic process [inference]

peptide hormone processing

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing

cellular developmental process [inference]

cell differentiation [inference]

cardiocyte differentiation [inference]

cardioblast differentiation

stem cell differentiation [inference]

cardioblast differentiation

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

cellular developmental process [inference]

cell differentiation [inference]

cardiocyte differentiation [inference]

cardioblast differentiation

stem cell differentiation [inference]

cardioblast differentiation

biological regulation [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing

Displaying **all 5** entries
GO Term	Evidence Code	Reference
Golgi membrane	ISS	GO_REF
Golgi membrane	IEA	GO_REF
plasma membrane	IBA	GO_REF
transport vesicle membrane	ISS	GO_REF
transport vesicle membrane	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane

bounding membrane of organelle [inference]

Displaying **all 5** entries
GO Term	Evidence Code	Reference
metalloendopeptidase activity	ISS	GO_REF
metalloendopeptidase activity	IBA	GO_REF
metalloendopeptidase activity	IEA	GO_REF GO_REF
methyltransferase activity
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
279	N-linked (GlcNAc...) asparagine			UniProt GlyGen
283	N-linked (GlcNAc...) asparagine			UniProt GlyGen
324	N-linked (GlcNAc...) asparagine			UniProt GlyGen
384	N-linked (GlcNAc...) asparagine			UniProt GlyGen
429	N-linked (GlcNAc...) asparagine			UniProt GlyGen
496	N-linked (GlcNAc...) asparagine			UniProt GlyGen
573		28510447 38253038	G49108TO	The O-GlcNAc Database
652	N-linked (GlcNAc...) asparagine			UniProt GlyGen
745	N-linked (GlcNAc...) asparagine			UniProt GlyGen
753	N-linked (GlcNAc...) asparagine			UniProt GlyGen