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Beta-2 adrenergic receptor

Summary

UniProt ID

P10608

Gene Symbol

Adrb2
Adrb2r

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P10608
Re-Glyco: P10608

Annotation

Keyword

Cell membrane
Disulfide bond
Endosome
G-protein coupled receptor
Glycoprotein
Golgi apparatus
Hydroxylation
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

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GO Term
nucleus
plasma membrane
membrane
axon
dendrite
receptor complex
postsynaptic membrane
presynapse
endosome
early endosome

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 57 in total

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GO Term
negative regulation of G protein-coupled receptor signaling pathway
negative regulation of smooth muscle contraction
positive regulation of transcription by RNA polymerase II
regulation of systemic arterial blood pressure by norepinephrine-epinephrine
cellular response to amyloid-beta
liver development
regulation of sodium ion transport
positive regulation of protein kinase A signaling
liver regeneration
transcription by RNA polymerase II

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GO Term
beta2-adrenergic receptor activity
B2 bradykinin receptor binding
epinephrine binding
norepinephrine binding
amyloid-beta binding
potassium channel regulator activity
enzyme binding
identical protein binding
protein homodimerization activity
protein-containing complex binding

Annotation information from UniProt.

Sequence

MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQAIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRFHAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRANLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNGRTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
6	N-linked (GlcNAc...) asparagine			UniProt
15	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Adrenoceptors	Rattus norvegicus
Cargo recognition for clathrin-mediated endocytosis	Rattus norvegicus
Clathrin-mediated endocytosis	Rattus norvegicus
G alpha (s) signalling events	Rattus norvegicus
Ub-specific processing proteases	Rattus norvegicus

Disease

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:11396	pulmonary edema	Alliance of Genome Resources
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources
DOID:3021	acute kidney failure	Alliance of Genome Resources
DOID:552	pneumonia	Alliance of Genome Resources
DOID:557	kidney disease	Alliance of Genome Resources
DOID:6000	congestive heart failure	Alliance of Genome Resources
DOID:820	myocarditis	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements