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Myeloperoxidase

Summary

UniProt ID: P11247
Gene Symbol: Mpo mKIAA4033
Gene ID: 17523
Organism: Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003347

GlyConnect

Myeloperoxidase

GlyGen

P11247

PubChem

P11247

Re-Glyco

P11247

Annotation

Keyword: Calcium Disulfide bond Glycoprotein Heme Hydrogen peroxide Lysosome Oxidation Reference proteome Signal

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	Reference
response to yeast	IMP	PMID
hypochlorous acid biosynthetic process	IMP	PMID
respiratory burst involved in defense response	IMP	PMID
response to oxidative stress	ISO	GO_REF
response to oxidative stress	IEA	GO_REF GO_REF GO_REF

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

respiratory burst involved in defense response

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

hydrogen peroxide catabolic process

biosynthetic process [inference]

small molecule biosynthetic process [inference]

hypochlorous acid biosynthetic process

reactive oxygen species biosynthetic process [inference]

hypochlorous acid biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

hypochlorous acid biosynthetic process

small molecule biosynthetic process [inference]

hypochlorous acid biosynthetic process

respiratory burst [inference]

respiratory burst involved in defense response

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

removal of superoxide radicals

hydrogen peroxide metabolic process [inference]

hydrogen peroxide catabolic process

reactive oxygen species biosynthetic process [inference]

hypochlorous acid biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

low-density lipoprotein particle remodeling

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

low-density lipoprotein particle remodeling

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

low-density lipoprotein particle remodeling

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

low-density lipoprotein particle remodeling

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to fungus [inference]

response to stimulus [inference]

response to stress [inference]

defense response [inference]

response to oxidative stress

response to external stimulus [inference]

response to mechanical stimulus

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to fungus [inference]

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

response to fungus [inference]

response to abiotic stimulus [inference]

response to mechanical stimulus

response to nutrient levels [inference]

response to food

response to chemical [inference]

response to food

response to lipid [inference]

response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to transition metal nanoparticle [inference]

response to gold nanoparticle

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
obsolete extracellular space
nucleoplasm	ISO	GO_REF
mitochondrion	HDA	PMID
secretory granule	ISO	GO_REF
secretory granule	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

azurophil granule

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

primary lysosome [inference]

azurophil granule

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

azurophil granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome [inference]

primary lysosome [inference]

azurophil granule

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

azurophil granule

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	Reference
peroxidase activity	ISS	GO_REF
peroxidase activity	ISO	GO_REF GO_REF GO_REF
peroxidase activity	IDA	PMID PMID PMID PMID PMID
peroxidase activity	IMP	PMID
peroxidase activity	IBA	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on peroxide as acceptor [inference]

peroxidase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

tetrapyrrole binding [inference]

heme binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

antioxidant activity [inference]

peroxidase activity

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKLLLALAGLLAPLAMLQTSNGATPALLGEVENSVVLSCMEEAKQLVDRAYKERRESIKRSLQSGSASPTELLFYFKQPVAGTRTAVRAADYLHVALDLLKRKLQPLWPRPFNVTDVLTPAQLNLLSVSSGCAYQDVRVTCPPNDKYRTITGHCNNRRSPTLGASNRAFVRWLPAEYEDGVSMPFGWTPGVNRNGFKVPLARQVSNAIVRFPNDQLTKDQERALMFMQWGQFLDHDITLTPEPATRFSFFTGLNCETSCLQQPPCFPLKIPPNDPRIKNQKDCIPFFRSCPACTRNNITIRNQINALTSFVDASGVYGSEDPLARKLRNLTNQLGLLAINTRFQDNGRALMPFDSLHDDPCLLTNRSARIPCFLAGDMRSSEMPELTSMHTLFVREHNRLATQLKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLGPAAMKKYLPQYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLNNQYRPTGPNPRVPLSKVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIVVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSEPLEPNGRVGQLLACLIGTQFRKLRDGDRFWWENPGVFSKQQRQALASISLPRIICDNTGITTVSKNNIFMSNTYPRDFVSCNTLPKLNLTSWKET

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
24				GlyGen
113	N-linked (GlcNAc...) asparagine			UniProt GlyGen
297	N-linked (GlcNAc...) asparagine			UniProt GlyGen
329	N-linked (GlcNAc...) asparagine		G62765YT	UniProt GlyGen
365	N-linked (GlcNAc...) asparagine		G80920RR	UniProt GlyGen
457	N-linked (GlcNAc...) asparagine	30899004	G74724QE G92275SC	GlycoProtDB UniProt GlyGen GlyConnect
527				GlyGen
711	N-linked (GlcNAc...) asparagine	30899004	G41247ZX G06110VR	UniProt GlyGen GlyConnect