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Cation-dependent mannose-6-phosphate receptor

Summary

UniProt ID

P11456

Gene Symbol

M6PR

Gene ID

281291

Organism

Bos taurus (domestic cattle)

External Links

PubChem: P11456
RaftProt: P11456
Re-Glyco: P11456

Annotation

Keyword: 3D-structure Disulfide bond Glycoprotein Lysosome Phosphoprotein Receptor Reference proteome Signal Transmembrane helix Transport

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	Reference
protein targeting to lysosome	IBA	GO_REF
protein targeting to lysosome	IEA	GO_REF
lysosomal transport	ISS	GO_REF
lysosomal transport	IEA	GO_REF
secretion of lysosomal enzymes

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

secretion of lysosomal enzymes

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein secretion [inference]

secretion of lysosomal enzymes

protein localization to organelle [inference]

protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to lysosome [inference]

protein targeting to lysosome

protein localization to extracellular region [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of localization [inference]

transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein secretion [inference]

secretion of lysosomal enzymes

secretion [inference]

secretion by cell [inference]

protein secretion [inference]

secretion of lysosomal enzymes

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

vacuolar transport [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

lysosomal transport

protein targeting to lysosome

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	Reference
lysosomal membrane	IEA	GO_REF
endosome	ISS	GO_REF
endosome	IEA	GO_REF GO_REF
late endosome	IBA	GO_REF
late endosome	IEA	GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

late endosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

late endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

late endosome

perinuclear region of cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	Reference
protein domain specific binding	IEA	GO_REF
retromer complex binding	IBA	GO_REF
retromer complex binding	IEA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

protein domain specific binding

protein-containing complex binding [inference]

retromer complex binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MMSPLHSSWRTGLLLLLLFSVAVRESWQTEEKTCDLVGEKGKESEKELALLKRLTPLFNKSFESTVGQSPDMYSYVFRVCREAGNHSSGAGLVQINKSNGKETVVGRFNETQIFNGSNWIMLIYKGGDEYDNHCGREQRRAVVMISCNRHTLADNFNPVSEERGKVQDCFYLFEMDSSLACSPEISHLSVGSILLVTLASLVAVYIIGGFLYQRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	Description	Source
59	N-linked (GlcNAc...) asparagine	UniProt
85	N-linked (GlcNAc...) asparagine	UniProt
96	N-linked (GlcNAc...) asparagine	UniProt
109	N-linked (GlcNAc...) asparagine	UniProt
115	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Cargo recognition for clathrin-mediated endocytosis	Bos taurus
Clathrin-mediated endocytosis	Bos taurus
Glycosphingolipid catabolism	Bos taurus
Lysosome Vesicle Biogenesis	Bos taurus
Retrograde transport at the Trans-Golgi-Network	Bos taurus

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UniCarb-DR

LM-GlycoRepo

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