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Integrin alpha-5
Summary
- UniProt ID
- P11688
- Gene Symbol
-
- Itga5
- Gene ID
- 16402
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003356
- GlyConnect
- GlyGen
- P11688
- PubChem
- P11688
- RaftProt
- P11688
- Re-Glyco
- P11688
Annotation
- Keyword
-
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Integrin
- Metal-binding
- Phosphoprotein
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum |
| Golgi apparatus |
| external side of plasma membrane |
| cell surface |
| focal adhesion |
| ruffle membrane |
| integrin alpha5-beta1 complex |
| glutamatergic synapse |
| plasma membrane |
| cell-cell junction |
| GO Term |
|---|
| calcium ion binding |
| integrin binding |
| epidermal growth factor receptor binding |
| signaling receptor activity |
Sequence
MGSWTPRSPRSPLHAVLLRWGPRRLPPLLPLLLLLWPPPLQVGGFNLDAEAPAVLSGPPGSLFGFSVEFYRPGRDGVSVLVGAPKANTSQPGVLQGGAVYVCPWGTSPIQCTTIQFDSKGSRILESSLYSAKGEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKDPQNDPVGTCYLSTENFTRILEYAPCRSDFGSAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQISESYYPEYLINPVQGQLQTRQASSVYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTVLNGSDIHSLYNVSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQRPAGIDPTPTLTLTGQDEFSRFGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGVVFIFPGGPGGLSTKPSQVLQPLWAAGRTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKALVYRGRPIISASASLTIFPSMFNPEERSCSLEGNPVSCINLSFCLNASGKHVPNSIGFEVELQLDWQKQKGGVRRALFLTSKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPKAPMDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLDVYGEKKHVYLGDKNALNLTFHAQNLGEGGAYEAELRVTAPLEAEYSGLVRHPGNFSSLSCDYFAVNQSRQLVCDLGNPMKAGTSLWGGLRFTVPHLQDTKKTIQFDFQILSKNLNNSQSNVVSFPLSVEAQAQVSLNGVSKPEAVIFPVSDWNPQDQPQKEEDLGPAVHHVYELINQGPSSISQGVLELSCPQALEGQQLLYVTKVTGLSNCTSNYTPNSQGLELDPETSPHHLQKREAPGRSSTASGTQVLKCPEAKCFRLRCEFGPLHRQESRSLQLHFRVWAKTFLQREYQPFSLQCEAVYEALKMPYQILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKLGFFKRSLPYGTAMEKAQLKPPATSDA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 87 | N-linked (GlcNAc...) asparagine |
|
||
| 185 | N-linked (GlcNAc...) asparagine | |||
| 300 | N-linked (GlcNAc...) asparagine |
|
||
| 310 | N-linked (GlcNAc...) asparagine |
|
||
| 319 | N-linked (GlcNAc...) asparagine |
|
||
| 381 |
|
|
||
| 527 | N-linked (GlcNAc...) asparagine |
|
||
| 533 | N-linked (GlcNAc...) asparagine |
|
||
| 596 | N-linked (GlcNAc...) asparagine | |||
| 612 | N-linked (GlcNAc...) asparagine |
G18647XP
G95177YH
G64527OM
G31852PQ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Mus musculus |
| Elastic fibre formation | Mus musculus |
| Fibronectin matrix formation | Mus musculus |
| GPER1 signaling | Mus musculus |
| Integrin cell surface interactions | Mus musculus |
| Signal transduction by L1 | Mus musculus |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | Mus musculus |
