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2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

Summary

UniProt ID: P11960
Gene Symbol: Bckdha
Gene ID: 25244
Organism: Rattus norvegicus (Norway rat)

External Links

GlyGen: P11960
PubChem: P11960
The O-GlcNAc Database: P11960
O-GlcNAcAtlas: P11960
Re-Glyco: P11960

Annotation

Keyword: Acetylation Magnesium Metal-binding Mitochondrion Oxidoreductase Phosphoprotein Potassium Reference proteome Thiamine pyrophosphate Transit peptide

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	Reference
response to nutrient	IEP	PMID
branched-chain amino acid catabolic process	ISS	GO_REF
branched-chain amino acid catabolic process	ISO	GO_REF
branched-chain amino acid catabolic process	IDA	PMID
response to glucocorticoid	IEP	PMID

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

sulfur compound metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA

catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

branched-chain amino acid catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process

branched-chain amino acid metabolic process [inference]

branched-chain amino acid catabolic process

lipid metabolic process [inference]

fatty acid derivative metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

branched-chain amino acid catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

branched-chain amino acid metabolic process [inference]

branched-chain amino acid catabolic process

carboxylic acid catabolic process [inference]

branched-chain amino acid catabolic process

branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

branched-chain amino acid catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA

purine-containing compound metabolic process [inference]

acyl-CoA metabolic process [inference]

fatty-acyl-CoA metabolic process [inference]

branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to nutrient levels [inference]

response to nutrient

response to chemical [inference]

response to nutrient

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organophosphorus [inference]

response to cAMP

response to nitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP

response to oxygen-containing compound [inference]

response to cAMP

Displaying **all 5** entries
GO Term	Evidence Code	Reference
mitochondrial matrix	ISS	GO_REF
mitochondrial matrix	IEA	GO_REF
branched-chain alpha-ketoacid dehydrogenase complex	ISS	GO_REF
branched-chain alpha-ketoacid dehydrogenase complex	ISO	GO_REF
branched-chain alpha-ketoacid dehydrogenase complex	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

oxidoreductase complex [inference]

alpha-ketoacid dehydrogenase complex [inference]

branched-chain alpha-ketoacid dehydrogenase complex

transferase complex [inference]

branched-chain alpha-ketoacid dehydrogenase complex

cellular anatomical structure [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

Displaying **all 5** entries
GO Term	Evidence Code	Reference
branched-chain 2-oxo acid dehydrogenase activity	ISS	GO_REF
branched-chain 2-oxo acid dehydrogenase activity	ISO	GO_REF
branched-chain 2-oxo acid dehydrogenase activity	IEA	GO_REF GO_REF
protein-containing complex binding	IPI	PMID
metal ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor [inference]

branched-chain 2-oxo acid dehydrogenase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

SAAKIWRPSRGLRQAALLLLGRPGARGLARFHPSRQQQQQFPSLDDKPQFPGASAEFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKLYRSMTLLNTMDRILYESQRQGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAGVLMYRDYPLELFMAQCYGNVSDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANQIVICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLLFSDVYQEMPAQLRRQQESLARHLQTYGEHYPLDHFDK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites