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MIRAGE
High affinity immunoglobulin epsilon receptor subunit alpha
Summary
- UniProt ID
- P12371
- Gene Symbol
- Fce1a Fcer1a
- Gene ID
- 25047
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- 3D-structure Alternative splicing Cell membrane Disulfide bond Glycoprotein IgE-binding protein Immunoglobulin domain Receptor Reference proteome Repeat Secreted Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| positive regulation of type I hypersensitivity | ||
| serotonin secretion | ||
| immune response | ||
| signal transduction | ||
| cell surface receptor signaling pathway |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| external side of plasma membrane |
| GO Term | Evidence Code | Reference |
|---|---|---|
| IgE receptor activity | ||
| high-affinity IgE receptor activity | ||
| high-affinity IgE receptor activity | ||
| high-affinity IgE receptor activity | ||
| IgE binding |
GO Hierarchy
Sequence
MDTGGSARLCLALVLISLGVMLTATQKSVVSLDPPWIRILTGDKVTLICNGNNSSQMNSTKWIHNDSISNVKSSHWVIVSATIQDSGKYICQKQGFYKSKPVYLNVMQEWLLLQSSADVVLDNGSFDIRCRSWKKWKVHKVIYYKDDIAFKYSYDSNNISIRKATFNDSGSYHCTGYLNKVECKSDKFSIAVVKDYTIEYRWLQLIFPSLAVILFAVDTGLWFSTHKQFESILKIQKTGKGKKKG
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 52 |
|
|
||
| 53 |
|
|
||
| 58 |
|
|
||
| 65 |
|
|
||
| 123 |
|
|
||
| 158 |
|
|
||
| 167 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| FCERI mediated Ca+2 mobilization | Rattus norvegicus |
| FCERI mediated MAPK activation | Rattus norvegicus |
| FCERI mediated NF-kB activation | Rattus norvegicus |
| Fc epsilon receptor (FCERI) signaling | Rattus norvegicus |
| Role of LAT2/NTAL/LAB on calcium mobilization | Rattus norvegicus |
