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Integrin beta-1-A

Summary

UniProt ID: P12606
Gene Symbol: itgb1-a
Gene ID: 397755
Organism: Xenopus laevis (African clawed frog)

External Links

Re-Glyco: P12606

Annotation

Keyword: Calcium Cell adhesion Cell junction Cell membrane Cell projection Disulfide bond EGF-like domain Glycoprotein Integrin Magnesium Metal-binding Myogenesis Phosphoprotein Receptor Reference proteome Repeat Signal Transmembrane helix

Gene Ontology (GO)

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GO Term	Evidence Code	Reference
cell-matrix adhesion	IBA	GO_REF
cell-matrix adhesion	IEA	GO_REF
integrin-mediated signaling pathway	IBA	GO_REF
integrin-mediated signaling pathway	IEA	GO_REF
muscle organ development

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

myoblast differentiation

cell motility [inference]

cell migration

cell-cell fusion [inference]

syncytium formation by cell-cell fusion [inference]

myoblast fusion

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

muscle organ development

muscle structure development [inference]

muscle organ development

cellular developmental process [inference]

cell differentiation [inference]

myoblast differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	Reference
focal adhesion	IBA	GO_REF
focal adhesion	IEA	GO_REF
integrin complex	IBA	GO_REF
integrin complex	IEA	GO_REF
cell surface	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

protein complex involved in cell adhesion [inference]

integrin complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

cleavage furrow

cell junction [inference]

synapse

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

leading edge membrane [inference]

ruffle membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

pigment granule [inference]

melanosome

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	Reference
fibronectin binding	IBA	GO_REF
fibronectin binding	IEA	GO_REF
integrin binding	IBA	GO_REF
integrin binding	IEA	GO_REF
protein kinase binding	IBA	GO_REF

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

fibronectin binding

signaling receptor binding [inference]

integrin binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

cytokine binding [inference]

chemokine binding [inference]

C-X3-C chemokine binding

laminin binding

cell adhesion molecule binding [inference]

integrin binding

cell adhesion mediator activity [inference]

cell-matrix adhesion mediator activity [inference]

collagen binding involved in cell-matrix adhesion

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

collagen binding [inference]

collagen binding involved in cell-matrix adhesion

extracellular matrix binding [inference]

laminin binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MAHYPVFTVGLLTCLVLCINAQQGGTECLKANAKSCGECIQAGPNCGWCTKVDFLQEGEPTSARCDDLAALKSKGCPEDDIQNPRGRKQKLKDIPITSKGKGERMDPANITQLRPQQMVFELRSGEPQTFNLTFRRAEDYPIDLYYLMDLSFSMKDDLENVKSLGTALMTEMEKITSDFRIGFGSFVEKTVMPYISTTPAKLINPCTSDQNCTSPFSYKNVLNLTKDGKLFNDLVGKQQISGNLDSPEGGFDAIMQVAVCGEQIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGKCHLHENMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEDFQPVYQELKNLIPKSAVGTLSSNSSNVIQLIIDSYNSLSSELILENSKLPEGVTISYKSFCKNGVKGTGEDGRKCSNISIGDQVEFEISVTAHKCPKKGQAESIKIKPLGFNEEVEIILQFLCECDCQDKGTPNSPECHFGNGTFECGACRCNDGRIGKECECSTDEVNSEDMDAYCRRENSSEICSNNGDCICGQCVCKKRDNPNEVYSGKYCECDNFNCDRSNGLICGGKGICKCRVCECFPNYSGSACDCSEDTSTCMAKNGQICNGRGICDCGRCKCTDPKFQGPTCELCQTCVGVCAEHKECVQCRAFQKGEKQDVCMEQCMHFNISLVDSREELPQPGQAEALTHCKEKDAEDCWFYFTYSVDSKNEVMVHVVKEPECPSGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 11 in total

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Position	Description	Source
109	N-linked (GlcNAc...) asparagine	UniProt
131	N-linked (GlcNAc...) asparagine	UniProt
211	N-linked (GlcNAc...) asparagine	UniProt
223	N-linked (GlcNAc...) asparagine	UniProt
268	N-linked (GlcNAc...) asparagine	UniProt
362	N-linked (GlcNAc...) asparagine	UniProt
416	N-linked (GlcNAc...) asparagine	UniProt
481	N-linked (GlcNAc...) asparagine	UniProt
520	N-linked (GlcNAc...) asparagine	UniProt
584	N-linked (GlcNAc...) asparagine	UniProt