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MIRAGE
5-aminolevulinate synthase, non-specific, mitochondrial
Summary
- UniProt ID
- P13196
- Gene Symbol
-
- ALAS1
- ALAS3
- ALASH
- OK/SW-cl.121
- Gene ID
- 211
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acyltransferase
- Alternative splicing
- Heme biosynthesis
- Hydroxylation
- Mitochondrion inner membrane
- Pyridoxal phosphate
- Reference proteome
- Transit peptide
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| mitochondrial inner membrane |
| mitochondrial matrix |
| nucleoplasm |
| cytosol |
| GO Term |
|---|
| 5-aminolevulinate synthase activity |
| pyridoxal phosphate binding |
| identical protein binding |
Sequence
MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 250 |
|
|||
| 575 |
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Heme biosynthesis | Homo sapiens |
| Mitochondrial protein degradation | Homo sapiens |
| PPARA activates gene expression | Homo sapiens |
| Transcriptional activation of mitochondrial biogenesis | Homo sapiens |
