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Ceruloplasmin

Summary

UniProt ID: P13635
Gene Symbol: Cp
Gene ID
Organism: Rattus norvegicus (Norway rat)

External Links

PubChem: P13635
Re-Glyco: P13635

Annotation

Keyword: 3D-structure Calcium Disulfide bond Glycoprotein Metal-binding Oxidoreductase Reference proteome Repeat Secreted Signal Sodium

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	Reference
liver development	ISO	GO_REF
liver development	IEP	PMID
intracellular copper ion homeostasis	ISS	GO_REF
intracellular copper ion homeostasis	ISO	GO_REF
intracellular iron ion homeostasis	ISS	GO_REF

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling [inference]

CAMKK-AMPK signaling cascade

metabolic process [inference]

catabolic process [inference]

lipid catabolic process

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

lipid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

lipid catabolic process

lipid modification [inference]

lipid oxidation [inference]

fatty acid oxidation

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

fatty acid metabolic process [inference]

fatty acid oxidation

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

cellular component assembly [inference]

protein-containing complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly

reproductive process [inference]

multi-organism reproductive process [inference]

female pregnancy

multicellular organismal process [inference]

multi-multicellular organism process [inference]

female pregnancy

tissue remodeling [inference]

mammary gland involution

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

lung development

gland development [inference]

liver development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

copper ion homeostasis [inference]

intracellular copper ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

intracellular iron ion homeostasis

copper ion homeostasis [inference]

intracellular copper ion homeostasis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to nutrient levels [inference]

response to nutrient

response to chemical [inference]

response to nutrient

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to metal ion [inference]

response to copper ion

response to nitrogen compound [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide hormone [inference]

response to insulin

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

copper ion transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

secretion [inference]

body fluid secretion [inference]

lactation

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

plasma membrane copper ion transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

calcium-mediated signaling [inference]

CAMKK-AMPK signaling cascade

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion [inference]

lactation

Displaying **all 3** entries
GO Term	Evidence Code	Reference
obsolete extracellular space
plasma membrane	IBA	GO_REF
cell surface	IDA	PMID

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	Reference
ferroxidase activity	ISS	GO_REF
ferroxidase activity	ISO	GO_REF
ferroxidase activity	IEA	GO_REF GO_REF
glutathione peroxidase activity	ISS	GO_REF
glutathione peroxidase activity	ISO	GO_REF

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on peroxide as acceptor [inference]

peroxidase activity [inference]

oxidoreductase activity, acting on metal ions [inference]

oxidoreductase activity, acting on metal ions, oxygen as acceptor

ferroxidase activity

binding [inference]

protein binding [inference]

protein-folding chaperone binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

antioxidant activity [inference]

peroxidase activity [inference]

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MKFLLLSALLFLHSSLAWTREKHYYIGITEAVWDYASGSEEKELISVDTEQSNFYLRNGPDRIGRKYKKALYSEYTDGTFTKTIDKPAWLGFLGPVIKAEVGDKVSVHVKNFASRPYTFHAHGVTYTKANEGAIYPDNTTDFQRADDKLFPGQQYLYVLRANEPSPGEGDSNCVTRIYHSHVDAPKDIASGLIGPLILCKKGSLHKEKEENIDQEFVLMFSVVDENLSWYLEDNIKTFCSEPEKVDKDNEDFQESNRMYSINGYTFGSLPGLSMCAEDRVKWYLFGMGNEVDVHSELFHGQALTSKNYHTDIINLFPATLIDVSMVAQNPGVWMLSCQNLNHLKAGLQAFFQVRDCNKPSPDDDIQDRHVRHYYIAAEETIWDYAPSGTDTFTGENFTSLGSDSRVFFEQGATRIGGSYKKLVYREYTDDSFTNRKERGPDEEHLGILGPVIWAEVGDIIRVTFHNKGQFPLSIQPMGVRFTKENEGTYYGPDGRSSKQASHVAPKETFTYEWTVPKEMGPTYADPVCLSKMYYSGVDLTKDIFTGLIGPMKICKKGSLLADGRQKDVDKEFYLFATVFDENESLLLDDNIRMFTTAPENVDKEDEDFQESNKMHSMNGFMYGNLPGLNMCLGESIVWYLFSAGNEADVHGIYFSGNTYLSKGERRDTANLFPHKSLTLLMTPDTEGSFDVECLTTDHYTGGMKQKYTVNQCKGQFEDVTLYQGERTYYIAAVEVEWDYSPSRDWEMELHHLQEQNVSNAFLDKEEFFIGSKYKKVVYREFTDSTFREQVKRRAEEEHLGMLGPLIHADVGAKVKVVFKNMATRPYSIHAHGVKTKSSTVAPTLPGEVRTYIWQIPERSGAGTEDSPCIPWAYYSTVDRVKDLYSGLIGPLIVCRKSYVKVFNPKKKMEFSLLFLVFDENESWYLDDNINTYPDHPEKDNKDNEEFIESNKMHAINGKMFGNLQGLTMHVGDEVNWYVMAMGNEIDLHTVHFHGHSFQYKHRGIHSSDVFDFFPGTYQTLEMFPQTPGTWLLHCHVTDHIHAGMVTTYTVLPNQETKSG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
138	N-linked (GlcNAc...) asparagine	UniProt
226	N-linked (GlcNAc...) asparagine	UniProt
396	N-linked (GlcNAc...) asparagine	UniProt
582	N-linked (GlcNAc...) asparagine	UniProt
756	N-linked (GlcNAc...) asparagine	UniProt
920	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Iron uptake and transport	Rattus norvegicus
Metal ion SLC transporters	Rattus norvegicus
Post-translational protein phosphorylation	Rattus norvegicus
Regulation of IGF Activity by IGFBP	Rattus norvegicus

Disease

Displaying 1 entry
DO ID	Disease Name	Source
DOID:4724	brain edema	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements