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Farnesyl pyrophosphate synthase
Summary
- UniProt ID
- P14324
- Gene Symbol
-
- FDPS
- FPS
- KIAA1293
- Gene ID
- 2224
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Cholesterol biosynthesis
- Cytoplasm
- Disease variant
- Host-virus interaction
- Hydroxylation
- Isoprene biosynthesis
- Magnesium
- Metal-binding
- Reference proteome
- Transferase
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| mitochondrial matrix |
| nucleoplasm |
| cytosol |
| peroxisome |
| GO Term |
|---|
| geranyl diphosphate biosynthetic process |
| farnesyl diphosphate biosynthetic process |
| cholesterol biosynthetic process |
| GO Term |
|---|
| metal ion binding |
| dimethylallyltranstransferase activity |
| geranyltranstransferase activity |
| RNA binding |
Sequence
MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 4 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of gene expression by SREBF (SREBP) | Homo sapiens |
| Cholesterol biosynthesis | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3805 | porokeratosis |
