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MIRAGE
Coagulation factor IX
Summary
- UniProt ID
- P16296
- Gene Symbol
- Cf9 F9
- Gene ID
- 24946
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
- Blood coagulation Calcium Cleavage on pair of basic residues Disulfide bond EGF-like domain Gamma-carboxyglutamic acid Glycoprotein Hydroxylation Magnesium Metal-binding Phosphoprotein Reference proteome Repeat Secreted Serine protease Signal Sulfation Zymogen
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| proteolysis | ||
| proteolysis | ||
| proteolysis | ||
| blood coagulation | ||
| blood coagulation |
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| obsolete extracellular space |
|
|
GO Hierarchy
| GO Term | Evidence Code | Reference |
|---|---|---|
| endopeptidase activity | ||
| endopeptidase activity | ||
| serine-type endopeptidase activity | ||
| serine-type endopeptidase activity | ||
| serine-type endopeptidase activity |
GO Hierarchy
Sequence
MADAPGLIPIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVQGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEHNIDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 78 |
|
|
||
| 92 |
|
|
||
| 199 |
|
|
||
| 208 |
|
|
||
| 214 |
|
|
||
| 216 |
|
|
||
| 226 |
|
|
||
| 307 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Amplification and propagation of coagulation cascade | Rattus norvegicus |
| FXIIa, PKa activate coagulation factors | Rattus norvegicus |
| Gamma-carboxylation of protein precursors | Rattus norvegicus |
| Initiation of coagulation cascade | Rattus norvegicus |
| Regulation of clotting cascade | Rattus norvegicus |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | Rattus norvegicus |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | Rattus norvegicus |
