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MIRAGE
Cytotoxic T-lymphocyte protein 4

Summary
UniProt ID
P16410
Gene Symbol
  • CD152
  • CTLA4
Gene ID
1493
Organism
Homo sapiens (human)
GlyGen
P16410
PubChem
P16410
Re-Glyco
P16410
Annotation
Keyword
  • 3D-structure
  • Adaptive immunity
  • Alternative splicing
  • Cell membrane
  • Diabetes mellitus
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Immunoglobulin domain
  • Pharmaceutical
  • Phosphoprotein
  • Reference proteome
  • Signal
  • Systemic lupus erythematosus
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 6 entries
GO Term
plasma membrane
Golgi apparatus
external side of plasma membrane
perinuclear region of cytoplasm
clathrin-coated endocytic vesicle
protein complex involved in cell adhesion
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
113 N-linked (GlcNAc...) asparagine
145 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
CTLA4 inhibitory signaling Homo sapiens
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) Homo sapiens
Disease
Displaying entries 41 - 43 of 43 in total
DO ID Disease Name Source
DOID:9538 multiple myeloma
DOID:9744 type 1 diabetes mellitus
DOID:986 alopecia areata
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025